Heart pump patients may get help from a surprising source

NCT ID NCT06510322

First seen Jan 24, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study tests whether sildenafil (a drug often used for erectile dysfunction) can reduce blood vessel damage in people with a left ventricular assist device (LVAD), a mechanical heart pump for advanced heart failure. About 50 adults with an LVAD will receive either sildenafil or a placebo. Researchers will use ultrasound and a tiny camera pill to check for changes in blood vessel stiffness and gut bleeding. The goal is to see if sildenafil can lower the risk of stroke and bleeding.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

Conditions

Explore the condition pages connected to this study.