Meyer Children's Hospital Irccs

This study is testing if adding a special skin glue helps keep IV lines in place better for children in the emergency room. Currently, IVs are held with a clear plastic dressing, but they can still slip out, which can be painful and require a new needle stick. Researchers will co…

This study aims to understand the broader effects of a powerful cystic fibrosis (CF) drug combination called ETI. Researchers will follow 150 people with CF, including children, who are starting this therapy. They will check how the drug changes metabolism, gut bacteria, and gene…

This study is testing whether a dietary supplement called L-serine can help improve overall health and daily functioning in children and young adults (ages 2-30) with rare genetic brain disorders known as GRIN-related disorders. Each participant will try both the L-serine supplem…

This study is testing whether a ketogenic diet (a high-fat, low-carb eating plan) can help control severe weight gain in children and young adults with brain tumors that affect appetite control. The weight gain is often caused by the tumor or its treatment and doesn't respond wel…

This study follows 500 children in Italy who had surgery for a rare birth defect affecting the anus and rectum. Researchers are comparing three different surgical techniques to see which one leads to better bowel control and fewer complications. They will track children's outcome…

This study looks back at medical records to see which prenatal ultrasound findings best predict which newborns will actually have an intestinal blockage after birth. Researchers will review data from about 60 newborns who had a suspected blockage seen on ultrasound during pregnan…

This study aims to see if training emergency room staff on the latest 2025 asthma guidelines leads to better care for children having severe asthma attacks. Researchers will observe 500 children, aged 6 to 17, who come to the emergency department. They will compare how well docto…

This study aims to compare two different scoring systems used to predict which children with Kawasaki Disease will not respond to the standard first treatment (IVIG). It involves 103 children under 18 from European and North Indian hospitals. The goal is to see how well these pre…

This study aims to better understand Behçet's disease in children by comparing them to adults with the same condition and healthy children. Researchers will collect blood samples to look for biological markers that might help identify the disease, track its activity, and distingu…

This study aims to better understand a rare, inherited condition caused by changes in the COL4A1 or COL4A2 genes. Researchers will observe and collect health information from families who carry these gene changes to learn how the disease affects different organs like the brain, e…

This study aims to better understand when to check children's heart rhythms for a rare but serious side effect linked to some psychiatric medications. Researchers will follow 100 children and teenagers starting these drugs, recording their heart activity at the start of treatment…

This study aims to gather detailed information about CACP syndrome, a very rare genetic disorder that causes bent fingers, stiff joints, hip problems, and sometimes heart inflammation in children. Researchers will collect health data from about 15 children across Europe to better…

This study aims to better understand chronic eye inflammation (uveitis) in children by tracking 290 patients over time. Researchers will observe how the disease progresses, how well different treatments work, and what factors affect vision outcomes. The goal is to gather informat…

This study aims to see if measuring a drug (infliximab) in saliva gives similar results to measuring it in blood for children with inflammatory bowel disease (IBD). Researchers will collect saliva and leftover blood samples from 15 children during their first few routine treatmen…

This study aims to understand if the community of bacteria in a child's gut is connected to brain tumors. Researchers will analyze stool samples from 100 children aged 3-18 who are suspected of having a brain tumor and are scheduled for surgery. The goal is to see if changes in g…

This study aims to understand the psychological factors behind unexplained physical symptoms like pain and fatigue in children and teens. Researchers will enroll 300 participants aged 11-17 who have these symptoms but no clear medical cause. They will use questionnaires and tests…

This international study aims to better understand a rare childhood condition called juvenile eosinophilic fasciitis, which causes painful muscle inflammation. Researchers will observe 20 children diagnosed since 2000 to document their symptoms, track how they respond to current …

This study aims to understand why children with short bowel syndrome (SBS) respond differently to a drug called teduglutide. Researchers will grow tiny, lab-made versions of a patient's intestine (organoids) from tissue samples taken during their standard surgeries. By testing th…

This study aims to better predict the long-term survival and quality of life for people with Erdheim-Chester disease (ECD), a very rare and complex condition. Researchers will analyze detailed medical information from up to 1,000 patients worldwide to identify which factors most …

This study is testing a new, radiation-free ultrasound technology called REMS to measure bone density in children aged 5-18. It aims to see how well this method works for kids with various conditions that can weaken bones, like osteoporosis or growth hormone deficiency. The goal …

Central nervous system tumours are the most common solid tumours and the leading cause of cancer mortality in children, with high biological and prognostic heterogeneity. Despite advances in the 2021 WHO molecular classifications, treatment options remain limited and often ineffe…