Mini-Organs shed light on why some kids respond better to gut drug

NCT ID NCT07400783

Recruiting now Knowledge-focused Sponsor: Meyer Children's Hospital IRCCS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why children with short bowel syndrome (a rare condition where part of the intestine is missing) respond differently to the drug teduglutide. Researchers will grow tiny, lab-made versions of the children's intestines (called organoids) from tissue samples taken during routine surgery. They will then treat these mini-intestines with teduglutide in a dish to see how they change. The goal is to find biological clues that explain why some children benefit more than others, which could lead to more personalized treatment in the future. No new treatments are given to the children themselves.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SHORT BOWEL SYNDROME (SBS) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

short bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SHORT BOWEL SYNDROME (SBS)

Contacts and locations

Show contact details

Locations

Aou Meyer IRCSS
RECRUITING

Florence, Florence, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••