New drug shows promise for managing short bowel syndrome Long-Term
NCT ID NCT07228403
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study looks at the long-term safety and effectiveness of a drug called glepaglutide in adults with short bowel syndrome (SBS), a condition where the body can't absorb enough nutrients from food. Participants who were already in earlier trials can continue treatment for up to 2 years. The goal is to see if the drug helps reduce the need for intravenous nutrition support and is safe over time.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AP-HP - Hôpital Beaujon
Clichy, Hauts-de-Seine, 92118, France
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Asklepios Klinik St. Georg
Hamburg, 20099, Germany
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Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, 10117, Germany
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Cleveland Clinic-9500 Euclid Ave
Cleveland, Ohio, 44195-0001, United States
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LHSC - University Hospital
London, Ontario, N6A 4V2, Canada
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Lied Transplant Center at Nebraska Medical Center
Omaha, Nebraska, 68105, United States
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Mayo Clinic - PPDS
Rochester, Minnesota, 55905-0001, United States
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Samodzielny Publiczny Szpitala Kliniczny im. Prof. Witolda Orlowskiego CMKP
Warsaw, Masovian Voivodeship, 00-416, Poland
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St Mark's Hospital (Central Middlesex Hospital)
Ealing, NW10 7NS, United Kingdom
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Szpital Skawina sp. z o.o. im. Stanley Dudricka
Skawina, Lesser Poland Voivodeship, 32-050, Poland
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UZ Leuven - PPDS
Leuven, 3000, Belgium
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Universitätsklinikum Bonn
Bonn, North Rhine-Westphalia, 53127, Germany
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Universitätsklinikum Frankfurt
Frankfurt am Main, Hesse, 60590, Germany
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Universitätsmedizin Rostock
Rostock, Mecklenburg-Vorpommern, 18057, Germany
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Vanderbilt University Medical Center-Tennesse-1211 21st Ave S
Nashville, Tennessee, 37212-2700, United States
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Wojewódzki Szpital Specjalistycznyo im. M. Pirogowa w Lodzi
Lodz, 90-531, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Mini-Organs shed light on why some kids respond better to gut drug
- Could a common diabetes drug help heal the gut in short bowel syndrome?
- New hope for kids with short bowel: can a drug cut the need for IV feeding?
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