Scientists hunt for hidden antibodies in Kids' kidney disease
NCT ID NCT07516964
First seen Apr 28, 2026 · Last updated Jun 24, 2026 · Updated 9 times
Summary
This study is investigating whether certain autoantibodies, especially those targeting a protein called nephrin, play a role in nephrotic syndrome, a kidney condition that causes swelling and protein loss in urine. Researchers will analyze blood and kidney tissue from 50 children and adults with the disease using advanced lab techniques. The goal is to better understand the disease mechanisms and pave the way for more personalized, effective treatments.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliero Universitaria Careggi
NOT_YET_RECRUITINGFlorence, Italy
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Azienda Ospedaliero Universitaria Pisana
NOT_YET_RECRUITINGPisa, Italy
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Azienda Ospedaliero-Universitaria di Parma
NOT_YET_RECRUITINGParma, Italy
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Azienda USL - IRCCS
NOT_YET_RECRUITINGReggio Emilia, Italy
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Bellvitge University Hospital
NOT_YET_RECRUITINGBarcelona, Spain
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Hospital General de México, Mexico City
NOT_YET_RECRUITINGMexico City, Mexico
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IRCCS Azienda Ospedaliero - Universitaria
NOT_YET_RECRUITINGBologna, Italy
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IRCCS Istituto Giannina Gaslini
NOT_YET_RECRUITINGGenova, Italy
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Ludwig-Maximilians Universitat
NOT_YET_RECRUITINGMünchen, Germany
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Mayo Clinic
NOT_YET_RECRUITINGRochester, Minnesota, 55902, United States
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Meyer Children's Hospital IRCCS
RECRUITINGFlorence, FIRENZE, 50139, Italy
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Ospedale S. Giovanni di Dio
NOT_YET_RECRUITINGFlorence, Italy
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Ospedale Santa Maria Annunziata
NOT_YET_RECRUITINGBagno a Ripoli, Firenze, Italy
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Ospedale Santo Stefano
NOT_YET_RECRUITINGPrato, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could lead to better diagnostic tests and more personalized treatments for children with nephrotic syndrome, reducing unnecessary steroid use.
What could go wrong
This is an observational study, not a treatment trial. It is small (50 participants) and early-stage, so findings may not apply to all patients or lead directly to new therapies.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.