New pill aims to plug protein leak in kidney patients

NCT ID NCT07614477

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called EVER001 in 45 adults with three types of kidney disease (FSGS, MCD, or IgA nephropathy) that cause protein to leak into urine. Participants take the drug twice daily for a year. The main goal is to see if it safely reduces protein levels and helps control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EVER001 (oral capsule, 200 mg twice daily)

What this could lead to

If successful, EVER001 could offer a new treatment option for people with certain kidney diseases, potentially reducing protein leakage and preserving kidney function.

What could go wrong

This is an early-phase study with only 45 participants, so results may not apply to everyone. The drug may cause side effects or fail to improve kidney health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

focal segmental glomerulosclerosis IgA glomerulonephritis lipoid nephrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Hebei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••