Mahidol University

This study tests whether a low-dose sugarcane-derived supplement called policosanol, combined with a structured exercise program, can improve physical fitness and blood lipid levels in adults with elevated cholesterol who do not yet need medication. Over 12 weeks, participants ar…

This phase III trial compares a shorter course of radiation therapy (hypofractionated) against the standard longer course for people with cervical cancer. Both groups also receive chemotherapy and brachytherapy. The goal is to see if the shorter schedule controls the cancer just …

This study tests whether adding stem cells to standard cooling therapy helps newborns with brain injury from lack of oxygen at birth. Forty infants will receive either stem cells from donated placentas or a placebo. Researchers will track death and developmental delays for up to …

This study compares the Invisalign Palatal Expander (IPE) with the Rapid Palatal Expander (RPE) in children aged 8–12 who have a narrow upper jaw and an underbite (skeletal Class III). Participants will wear a facemask after expansion. Researchers use 3D X-rays to measure changes…

This study compares standard beta-lactam antibiotics alone versus beta-lactam plus levofloxacin in adults with streptococcal bacteremia (bacteria in the blood). 165 participants will be randomly assigned to receive either the combination or monotherapy. The goal is to see if addi…

This study tests whether giving extra human albumin—a natural blood protein—along with standard care can help people survive septic shock after surgery. Septic shock is a life-threatening condition where infection causes dangerously low blood pressure. The trial will enroll 304 a…

This study tests whether the drug aminophylline can protect the kidneys of children receiving cisplatin chemotherapy. Twenty-four children will be randomly assigned to receive either aminophylline or a placebo alongside their standard chemo hydration. Researchers will measure kid…

This study explores whether a digital infrared camera, which measures skin temperature, can help diagnose carpal tunnel syndrome (CTS). Researchers will compare temperature patterns in the hands of people with CTS to standard electrodiagnostic tests. The goal is to see if thermog…

This study compares Pilates to walking in 34 sedentary adults aged 18-59 who sit for over 7 hours daily. Participants will do supervised 1-hour sessions to see if Pilates improves core muscle thickness, strength, flexibility, endurance, balance, and posture. The goal is to find a…

This study tests whether artificial intelligence can help teens with idiopathic scoliosis improve their posture. Thirty participants aged 10–18 will receive either standard physical therapy or additional AI-based feedback on their body alignment. The goal is to see if the AI guid…

This trial tests whether a one-minute suction of the airway leading to the surgical lung helps it collapse faster and more completely during uniportal video-assisted thoracoscopic surgery (U-VATS). Good lung collapse gives the surgeon a clearer view and may reduce complications. …

This study tests whether a nerve block injection at the back of the head can help people with migraine who overuse painkillers. The injection contains lidocaine and a steroid. 130 participants will receive either the active injection or a placebo. Researchers will track headache …

This study tests whether a 14-day course of the antibiotic rifaximin can reduce bothersome bloating in adults with irritable bowel syndrome, functional constipation, or similar gut disorders. About 78 participants will receive either rifaximin or a placebo, and researchers will m…

This study tests two non-invasive treatments for plantar fasciitis, a common cause of heel pain. 28 adults will receive either high-intensity laser therapy or focused shock wave therapy, plus exercises. Researchers will measure pain and foot function over 12 weeks to see which wo…

This study tests whether a sleep medication called lemborexant can help older adults in the intensive care unit (ICU) sleep better and reduce their risk of delirium, a state of sudden confusion. The trial will involve 100 patients aged 65 and older who are in the surgical ICU. Pa…

This study tests a new care program for older adults in Thailand who have had a heart attack. The program combines in-person education, motivational counseling, and a mobile app to help them adopt healthy habits and track their recovery. Researchers will measure if this approach …

This study tests whether a computer-based stepping game, called Smart±step, can help older adults with mild cognitive impairment (MCI) improve their balance, thinking, and quality of life while reducing their risk of falling. About 70 participants will use the game, which combine…

This study is creating a new questionnaire to measure how well children recover after anesthesia and surgery. Researchers will work with 200 children aged 2-17 and their parents to develop and test the tool. The goal is to provide a simple, child-friendly way to assess recovery q…

This study will use a simple brain wave monitor (BIS) to track brain activity in 40 critically ill ICU patients—some with decreased consciousness and some without. The goal is to see if BIS readings can predict how long patients stay in the ICU, whether they survive, and their re…

This study will use echocardiograms (heart ultrasounds) to see how the heart responds to two common treatments for septic shock: intravenous fluids and vasopressors (medicines that raise blood pressure). Researchers will measure changes in heart function before and 15 minutes aft…

This study will test whether mild electrical brain stimulation, combined with physical therapy, changes brain activity in people who had a stroke. Sixty participants will receive either direct or alternating current stimulation during rehab sessions. Researchers will measure bloo…

This study looks at how the amount of deep sleep just before waking affects how alert people feel after a 2-hour nap taken at night. Researchers will monitor brain activity during sleep and test reaction times after waking. The goal is to understand sleep inertia and improve nap …