Mahidol University

This study compares two ways to prevent repeat urinary tract infections (UTIs) in women after menopause. One group takes a nightly antibiotic pill for 6 months, while the other uses a vaginal tablet containing a probiotic (Lactobacillus) and a tiny amount of estrogen. The goal is…

This study tests whether a personalized home exercise routine can prevent joint and muscle pain in early breast cancer patients who are starting a common hormone therapy (aromatase inhibitors). About 200 participants will be randomly assigned to either the exercise program or usu…

This phase 2 trial tests whether a combination of olanzapine and ondansetron can prevent nausea and vomiting caused by high-dose cisplatin chemotherapy in people with solid tumors. The approach aims to reduce steroid use by omitting dexamethasone on days 2 through 4. The study en…

This study is testing whether a daily capsule of holy basil extract can reduce stomach inflammation and improve symptoms like pain, bloating, and nausea in adults with indigestion. Twenty-seven participants will take the supplement for 28 days and undergo endoscopies and blood te…

This study tests whether a gentle electrical current applied to the brain, combined with walking and thinking exercises, can improve movement and thinking in people who have had a stroke. Sixty adults who had a stroke between 2 weeks and 5 years ago will participate. The goal is …

This study looks at whether not suctioning the breathing tube before removing it is safe and might reduce coughing and sore throat. About 408 adults having planned surgery will be randomly assigned to either routine suctioning or no suctioning. The main goal is to see if oxygen l…

This study tests whether a faster rehabilitation program helps people recover better after total knee replacement surgery. Researchers will compare the accelerated program to standard rehab in 32 adults aged 50-80. The goal is to see if the faster approach improves knee function …

This study aims to create and test a Thai version of a questionnaire that measures how well children recover after surgery. Researchers will translate the original English tool, adapt it for Thai culture, and then test it with 130 children aged 2-17 at Siriraj Hospital. The goal …

This study creates a registry to collect data on dengue infections in people with congenital bleeding disorders like hemophilia. Dengue can cause serious bleeding, and those with bleeding disorders may face higher risks. The goal is to understand bleeding complications, treatment…

This study looks at how well a single-shade composite resin matches the color of natural front teeth in children aged 6-15 who have lost part of a tooth from injury. Researchers will check color match and stability at 6 and 12 months, and ask kids and parents how satisfied they a…

This study looks at how exercise affects blood components and physical fitness in overweight or obese adults. Researchers will measure things like body fat, strength, and heart health, along with tiny particles in the blood. The goal is to learn more about how exercise helps the …

This study looks back at medical records of 648 women who had heavy bleeding after a C-section. Researchers want to see how often the drug tranexamic acid (TXA) was given over the years, and whether more use led to better outcomes like less blood loss or fewer transfusions. The g…

This study compares two common risk assessment tools—the Charlson Comorbidity Index (CCI) and the POSSUM score—to see which better predicts complications in women undergoing surgery for gynecologic cancers. Researchers will track complications, hospital stay length, and 30-day de…

This study tests whether doing a specific knee exercise with a metronome (a device that makes regular beeps) can improve how the thigh muscle works in athletes who recently had ACL reconstruction. 40 participants will do one session of the exercise, with or without the metronome.…

This study looks at how the breathing drive and effort of patients in the ICU change when the ventilator pressure support is adjusted. Forty adults who had major abdominal surgery and are on a breathing machine will have their ventilator settings changed in small steps. Researche…