Mahidol University

This trial tests a new technique for placing self-gripping mesh during laparoscopic inguinal hernia repair. Instead of folding the mesh directly, surgeons wrap it in a plastic sheath to make insertion smoother and reduce the risk of the mesh sticking prematurely. The study compar…

This study tests a new way to help informal workers (like street vendors and farmers) in Thailand quit smoking. Trained village health volunteers provide advice and support, while participants also get messages and counseling through the Line app and a telephone Quitline. The pro…

This study looked at whether eating a plant-based diet for 12 weeks could lower blood pressure and change gut bacteria in 102 kidney transplant recipients. Participants either followed a plant-based diet or their usual diet. The goal was to see if this diet could help manage hear…

This study tested whether giving iron supplements daily or weekly works better to prevent anemia in healthy Thai infants aged 6 to 12 months. A total of 287 babies were randomly assigned to receive iron daily or weekly for 3 months, then all switched to weekly for another 3 month…

This study tested an online family education program delivered via a messaging app to help families of people with first-episode schizophrenia. The goal was to reduce negative emotions in family members and improve how consistently patients take their medication. 53 patients and …

This study tested a treatment called oral immunotherapy for people with shrimp allergy. 20 participants aged 12-40 with confirmed shrimp allergy were given increasing amounts of shrimp over time to see if they could tolerate more shrimp without a reaction. The main goal was to me…

This study tested a new, locally made capsule to see if it can accurately diagnose slow-transit constipation. Twenty healthy volunteers and people with constipation took both the new capsule and a standard capsule at the same time. After five days, an abdominal X-ray counted how …

This study tested a Thai version of a simple tool called the Delirium Diagnostic Tool-Provisional (DDT-Pro) to see if it can accurately diagnose delirium in elderly patients with hip fractures. Delirium is a common complication after hip fracture surgery, but current diagnostic m…

This study looked at whether offering HIV self-testing with online supervision helps young men who have sex with men (MSM) in Ho Chi Minh City get tested more often. One hundred participants aged 16-29 either used the supervised self-test or answered a simple yes/no about past te…

This study tested a program called HUG-M+ designed to help young Thai men who have sex with men get tested for HIV and reduce risky behaviors. Over 600 men aged 15-29 took part in two cities, one receiving the program and the other standard care. The goal was to see if the progra…

This study looked at whether adding change-of-direction drills to the FIFA 11+ warm-up program can reduce a risky knee movement called knee valgus angle in male soccer players. Twelve players were split into two groups: one did the FIFA 11+ alone, the other added change-of-direct…

This study compared telemedicine follow-ups to standard in-person clinic visits for cancer patients with chronic pain. Researchers measured how much pain interfered with daily activities using a standard questionnaire. The goal was to see if remote care could be as effective and …

This trial investigates whether custom foot orthoses (shoe inserts) with or without special wedges can reduce pain and improve foot function in people with plantar heel pain (plantar fasciitis). Participants are randomly assigned to one of three orthosis types and are monitored d…

This study explores whether a mixed reality exergame—a video game that combines physical movement—can help older adults with mild cognitive impairment (MCI) improve their thinking skills and motivation to exercise. Participants play a balloon-popping game using special glasses th…

This study tested whether a device that sends magnetic pulses to shoulder muscles can help stroke patients with a dislocated shoulder. Twenty people in the subacute phase of stroke received either real or fake magnetic stimulation for 20 minutes a day, 5 days a week, for 2 weeks,…

This study tested whether a gentle electrical current applied to the scalp (tES) can improve movement and thinking in people who had a stroke. Sixty adults who had a stroke between 2 weeks and 2 years ago received real or fake stimulation while doing physical therapy. Researchers…

This study looked at whether a low-dose vaginal estrogen tablet could improve overactive bladder symptoms in menopausal women by changing the bacteria in their urine. Thirty women used the tablet daily for two weeks, then twice a week for 12 weeks. Researchers measured changes in…

This study compared two treatments for myofascial pain syndrome in the upper trapezius muscle: focused shockwave therapy and dry needling. Fifty-three adults with chronic shoulder pain received either three weekly shockwave sessions or dry needling. Researchers measured pain leve…

This study looked at whether children with year-round allergic rhinitis can use a nasal steroid spray only when symptoms bother them, instead of every day. Sixty-eight children aged 6 to 18 were randomly assigned to either daily use or as-needed use of fluticasone furoate spray. …

This study tested whether adding a gentle brain stimulation technique (tDCS) to physical therapy could improve walking, balance, and leg strength in people who had a stroke. 34 adults with sub-acute or chronic stroke participated. The goal was to see if this combination helps the…

This study tested whether a smartphone app with video guidance helps patients prepare better for a colonoscopy compared to standard instructions. 488 adults were randomly assigned to use the app or receive usual education. The goal was to see if the app leads to cleaner bowels, m…

This study tested whether adding hyaluronic acid to a ketorolac injection helps frozen shoulder more than ketorolac alone. Fifty-six adults with frozen shoulder received one shot of either the combination or just ketorolac, then followed a rehab program. After 24 weeks, both grou…

This study examines why some high-risk patients develop central line infections after getting a PICC (a type of long-term IV). Researchers will review medical records from over 1,200 patients to see if low hemoglobin levels or how often blood is drawn from the line play a role. T…

This study tested whether a sing-along song can help visually impaired individuals aged 6 to 20 learn to brush their teeth better. Forty participants in Nepal were split into two groups: one received standard audio-tactile instruction, and the other heard a song with the same ins…

This study tested whether giving a gas sedative (isoflurane) instead of standard IV drugs could reduce the energy delivered to the lungs by the breathing machine in 40 ICU patients. The goal was to see if this approach might lower the risk of lung injury. The trial was small and …

This study examined 236 adults in a surgical intensive care unit who needed a breathing machine for more than 4 days. Researchers wanted to see if the length of time a patient had anemia (low red blood cells) was linked to how long they stayed on the ventilator. The goal was to b…

This study looked at 120 adults with inflammatory bowel disease (IBD) to see if simple stool tests can tell if the disease is active or in remission, just like a colonoscopy does. Colonoscopy is the current gold standard but is expensive, invasive, and not ideal for frequent chec…

This completed study tested whether machine learning could predict dengue and severe dengue using electronic health records from 1,000 patients in Thailand and Vietnam. The goal was to create a low-cost tool that works even when lab tests are unavailable. Researchers used vital s…

This study tested whether a triple-headed toothbrush removes more dental plaque than a regular single-headed toothbrush when parents brush the teeth of preschool children with developmental disabilities. Twenty-four children aged 3 to 6 years participated, and each child tried bo…

This completed study from Mahidol University looked at how often women who received epidural pain relief during labor ended up having a cesarean delivery. Researchers tracked 188 women and also examined factors like cervical dilation and side effects. The goal was to better under…

This study reviewed the medical records of 649 women who had heavy bleeding (at least 1 liter) after a C-section. Researchers looked at how many needed blood transfusions, intensive care, or other treatments. The goal was to better understand what happens to these patients, not t…

This completed study looked at how common poor sleep is after a C-section when spinal morphine is used for pain relief. Researchers followed 286 mothers and measured sleep quality, pain, nausea, and itching on the first night after surgery. The goal was to understand which factor…

This study looked at whether an Obstetric Comorbidity Index can predict severe health problems in women who had a C-section and experienced heavy bleeding. Researchers reviewed the records of 583 patients to see how well the index identified those at highest risk. The goal is to …