Could stem cells save Babies' brains after oxygen loss?
NCT ID NCT07018739
First seen Jun 24, 2026 · Last updated Aug 13, 2026 · Updated 6 times
Summary
This study tests whether adding stem cells to standard cooling therapy helps newborns with brain injury from lack of oxygen at birth. Forty infants will receive either stem cells from donated placentas or a placebo. Researchers will track death and developmental delays for up to two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Wharton's jelly-derived mesenchymal stem cells (MSCs)
- What this could lead to
- If it works, this could point toward a treatment that reduces the risk of death or long-term disability in newborns with brain injury from oxygen loss.
- What could go wrong
- This is an early Phase 1/2 trial with only 40 infants, so results are preliminary. The stem cell approach may not improve outcomes over cooling alone, and there are risks like infection or infusion reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Siriraj Hospital, Mahidol University
Bangkok, 10700, Thailand
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