Centre For Addiction And Mental Health

This study tests a non-invasive brain stimulation technique to boost memory and thinking in 150 older adults with mild cognitive impairment (MCI), a condition that often leads to Alzheimer's. The goal is to strengthen the brain's natural ability to compensate for early damage and…

This study tests a structured care plan for treating agitation and aggression in people with Alzheimer's disease. The plan combines medications and non-drug approaches based on regular assessments. Researchers will compare this approach to usual care in 187 participants living in…

This 7-year study tests whether a combination of gentle brain stimulation (tDCS) and computer-based cognitive training can slow memory loss and prevent Alzheimer's dementia. It involves 375 older adults with mild cognitive impairment or a history of depression. Participants recei…

This study is testing a home-based program designed to help prevent long-term memory decline in older adults at risk for Alzheimer's disease. The program combines brain-training exercises with a gentle, non-invasive brain stimulation technique called tDCS, which is delivered by a…

This pilot study tests a therapy called Narrative Enhancement and Cognitive Therapy (NECT-Y) to see if it can reduce self-stigma in youth aged 14-29 with bipolar disorder or multiple mental health conditions. About 96 participants will either join a 14-week virtual group therapy …

This study tests a 4-session psychological treatment for people with borderline personality disorder (BPD) who visit the emergency department with suicidal thoughts or self-harm. The goal is to see if this brief therapy can reduce suicidal thinking, improve symptoms, and lower th…

This study aimed to see if online group therapy (CBT with mindfulness) works as well as in-person therapy for adults with major depression. It planned to include about 200 participants and compare changes in depression and anxiety scores. However, the study was withdrawn before e…

This study looks at whether 8 weeks of daily computer-based cognitive training, sometimes paired with a gentle brain stimulation technique called tDCS, can improve thinking, balance, and daily living skills in seniors aged 50+ with mental health conditions. Participants live in c…

This study tests a telephone-based, computer-aided care program for adults with depression, anxiety, or risky drinking. Participants receive extra support from a Mental Health Technician who helps their primary care provider manage treatment. The goal is to see if this approach r…

This study looks at whether a new way of delivering care—called an Integrated Collaborative Care Team (ICCT)—helps youth aged 14-17 with mental health and addiction issues get faster, more effective support. About 247 teens will be randomly assigned to either the ICCT model or us…

This study looks at how a non-invasive brain stimulation technique called paired associative stimulation (PAS) affects working memory in people with schizophrenia. Researchers will use brain scans (EEG) and memory tasks to measure changes over one week. The goal is to understand …

This small study tests whether psilocybin, the active ingredient in magic mushrooms, can increase the number of connections between brain cells in people with mild memory problems. Ten participants (six with amnestic mild cognitive impairment and four healthy volunteers) will rec…

This study tests whether a 12-week program that combines brain training, social activities, and exercise can help seniors with mental health conditions living in community housing. The program involves 18 participants working in small groups with a support worker. The goal is to …

This study looks at whether people with anorexia nervosa can learn to associate positive feelings with food-related cues. Researchers will measure brain activity, heart rate, and pupil responses in 90 female participants aged 12-22 to understand how reward learning works and whet…

This study planned to test a digital health worker named PAHOLA that would deliver counseling to people who drink too much alcohol but face barriers to getting treatment. The goal was to see if talking to a computer-based helper could reduce drinking and improve health. However, …

This study looks at whether Black, Indigenous, and People of Color (BIPOC) face more barriers to starting or sticking with antidepressants after a one-time psychiatric consultation for depression. Researchers will survey 60 adults diagnosed with depression three months after thei…

This study aimed to develop and test a mental health program designed specifically for young South Asian women aged 16-24 with mood or anxiety disorders. The program was meant to be culturally sensitive and last 12 weeks, with researchers tracking changes in mood, self-esteem, an…

This study looks at why people with Alzheimer's and other dementias become agitated or aggressive. Researchers will use gentle magnetic and electrical brain stimulation to understand the brain changes behind these symptoms. They will also test if a mild electrical current (tDCS) …