Online therapy vs. In-Person: which works better for depression?

NCT ID NCT04825535

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to compare online group cognitive behavioral therapy (CBT) with in-person group CBT for adults with major depression. The goal was to see if online therapy is just as effective and more cost-effective. However, the trial was withdrawn before enrolling any participants, so no data were collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cognitive behavioral therapy with mindfulness (CBT-M)

What this could lead to

If successful, this could show that online CBT-M is as effective as in-person therapy, making treatment more accessible and affordable for people with depression.

What could go wrong

The trial was withdrawn before any participants enrolled, so no results are available. Online therapy may not work as well for everyone, and the study's non-inferiority design requires careful interpretation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    Toronto, Ontario, M6J 1H4, Canada