Magic mushroom compound tested for depression in autism

NCT ID NCT06731621

First seen Feb 01, 2026 · Last updated May 17, 2026 · Updated 14 times

Summary

This early-phase study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy is safe and tolerable for autistic adults with depression that hasn't responded to other treatments. Twenty participants will receive two doses (10mg and 25mg) along with about 20 hours of therapy. The study also uses brain scans to understand how psilocybin may affect brain networks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.