Centre For Addiction And Mental Health

This study tested whether adding the antibiotic minocycline to standard antidepressant medication helps people with treatment-resistant depression. In this 12-week trial, 76 adults who hadn't responded well to their current antidepressants were randomly assigned to receive either…

This study tested whether an online cognitive behavioral therapy (CBT) program, with or without one-on-one peer support, helps people reduce their substance use. It involved 198 adults already receiving standard addiction treatment. Researchers compared three groups over eight we…

This study tested a medication called cytisine to help people who want to quit smoking and also have alcohol use disorder. It involved 20 adults and aimed to see if the drug was safe and effective for this group. The trial measured how well participants could stop smoking and man…

This study tested a 4-week virtual intensive outpatient program for adults with moderate to severe alcohol use disorder who wanted to stop drinking. The program included daily group and individual therapy, medication management, and required participants to use a breathalyzer mul…

This study tested if sending supportive text messages could help young people with psychosis get from the emergency room to their first follow-up appointment. Researchers enrolled 186 young adults (ages 16-29) to see if reminders and check-ins via text improved attendance at that…

This study tested a new parenting program designed specifically for parents who are depressed and have children with emotional or behavioral problems. The goal was to see if the program was practical to run and acceptable to parents, and if they would stick with it. Researchers w…

This study aimed to understand if the brain's response to insulin is different in teens with depression. Researchers compared brain scans of 12 adolescents with depression to 12 healthy teens after giving them a nasal spray containing either insulin or a placebo. The goal was to …

This study aimed to understand how a synthetic cannabis-like drug called nabilone affects certain chemicals in the brain of healthy people. Researchers used brain scans (MRI and PET) to measure changes before and after participants took a one-week, low-dose course of nabilone. Th…

This study aimed to understand which children with disruptive behavior disorders respond best to standard treatments. Researchers collected psychological and emotional information from 600 children (ages 6-12) and their parents before and after therapy programs. They tested wheth…

This study tested a new social-emotional learning program called EMPOWER in after-school settings. Researchers wanted to see if the program was practical to run and if it helped 11-14 year olds improve skills like self-awareness and resilience. They compared the new program to th…

This study aimed to understand how a noninvasive brain stimulation technique might affect visual processing in adults with body dysmorphic disorder (BDD). Researchers tested two types of magnetic stimulation on 40 participants to see if it changed how their brains processed image…

This study tested two different patterns of non-invasive brain stimulation on healthy volunteers to see which one better strengthens brain connections, a process called plasticity. Researchers compared a standard pattern used to treat depression against a new, spaced-out pattern.…

This study tested a new social-emotional learning curriculum designed to be added to an existing STEM after-school program. Researchers wanted to see if the program was practical to run and if it helped improve the social skills, resilience, and overall well-being of the 11-14 ye…