Centre For Addiction And Mental Health

This study tested a 4-week virtual intensive outpatient program for 63 adults with moderate to severe alcohol use disorder. The program included group therapy and daily breathalyzer checks, all done from home. Researchers measured how many people stayed in the program and how sat…

This study tested whether cytisine, a plant-based medication, is safe and helpful for quitting smoking in people who also have alcohol use disorder. Twenty adults who smoked daily and had alcohol problems took cytisine and were monitored for side effects and smoking abstinence. T…

This study compares a 6-month version of dialectical behaviour therapy (DBT) to the standard 1-year program for people with borderline personality disorder who repeatedly self-harm. Researchers want to see if the shorter treatment is just as good at reducing self-harm and is more…

This study looked at 600 children with disruptive behavior disorders like ADHD or oppositional defiant disorder. Researchers created personal profiles of each child and their parent to see if they could predict which type of therapy—child counseling or parent training—would work …

This study tested an online therapy program called Breaking Free Online for people with substance use disorder. 198 adults from an addiction clinic were split into three groups: standard care with group support, the online program alone, or the online program plus one-on-one peer…

This study tested whether adding the antibiotic minocycline to usual treatment could ease depression in people whose depression didn't get better with standard antidepressants. 76 adults took either minocycline or a placebo for 12 weeks. The goal was to see if the drug reduced de…

This study looked at whether a version of cognitive behavioral therapy (CBT) adapted for South Asian culture could help reduce depression and anxiety. About 146 Canadian adults of South Asian origin with mild to severe symptoms took part. Researchers worked with community members…

This study tested a new group therapy for depressed parents of children aged 6 to 10 with emotional or behavioral issues. The goal was to see if the therapy was practical and well-liked by parents. The results will help design a larger study to see if this approach can improve bo…

This study tested a friendly healthbot designed to help people remember to take their smoking cessation medication (varenicline). Researchers interviewed smokers and healthcare providers to understand challenges, then built a chatbot. 40 participants used the bot for 12 weeks, an…

This study tested a culturally adapted version of cognitive behavioral therapy (CA-CBT) for Chinese youth aged 12 to 21 in Ontario who have anxiety or depression. The goal was to make treatment more relevant and accessible. Researchers measured changes in symptoms and satisfactio…

This study tested whether sending text message reminders helps young people (ages 14-35) with psychosis attend their first appointment at an early psychosis program after being seen in the emergency room. Researchers enrolled 186 participants and tracked whether they showed up fo…

This study looked at how two different patterns of non-invasive brain stimulation (called iTBS) affect brain plasticity—the brain's ability to change and adapt. Twenty-nine healthy, right-handed adults aged 18 to 50 took part. Researchers compared a standard pattern used for depr…

This study looked at how a noninvasive brain stimulation technique called TMS changes the way people with body dysmorphic disorder (BDD) process visual information. Forty adults with BDD or mild symptoms received TMS followed by brain scans while viewing faces. The goal was to un…

This study looked at how nabilone, a cannabis-like drug, changes a brain enzyme called FAAH in 10 healthy adults. Participants took nabilone for one week and had brain scans before and after. The goal was to understand how the drug affects the body's natural cannabis system, not …

This study tested a mobile app called App for Independence-O (A4i-O) in 14 adults with opioid use disorder. Participants used the app for one month to see if it was easy to use and helpful. The goal was to gather feedback and check how the app works before larger studies.

This study followed 51 people with schizophrenia who were already stable on long-acting injectable antipsychotics for 48 weeks. Researchers wanted to see how often psychotic symptoms return when patients take their medication as prescribed. They also checked blood levels of the d…

This study looked at whether a new social-emotional learning program could work in a STEM after-school program for kids aged 11-14. Researchers checked if the program was easy to use and if it helped kids build skills like self-awareness, resilience, and overall well-being. About…

This study tested whether a special anti-stigma program for healthcare workers improves their attitudes toward people with mental health or substance use problems. About 485 staff and clients from six health centers took part—three centers got the program, three did not. Research…

This study looked at whether psilocybin (the active ingredient in magic mushrooms) needs to cause psychedelic effects to help with depression. 41 adults with treatment-resistant depression were given either psilocybin alone, psilocybin plus risperidone (a drug that blocks the psy…

This study tested a year-long support program called HOP-C for young people (ages 16-25) who recently moved into stable housing after being homeless. The program combined case management, peer support, and mental health help. Researchers compared their outcomes to those receiving…

This study looked at whether brain insulin resistance plays a role in depression during adolescence. Researchers used MRI scans to compare brain activity in 24 teens with and without depression after they received insulin or a placebo through a nasal spray. The goal was to unders…

This study looked at whether a program called NAVIGATE helps youth (ages 14-35) having their first episode of psychosis get better coordinated care. Researchers worked with 100 participants across Ontario to see if the program reduces hospital stays and ER visits. The goal was to…

This study tested a new social-emotional learning program called EMPOWER in after-school programs for youth aged 11-14. Researchers wanted to see if the program was easy to use and if it helped improve teens' social-emotional skills, resilience, and overall well-being. About 218 …