New care pathway aims to tame agitation in Alzheimer's without overmedicating

NCT ID NCT03672201

Ongoing Symptom relief Sponsor: Centre for Addiction and Mental Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a structured care pathway for treating agitation and aggression in people with Alzheimer's disease. The pathway combines personalized activities with medication guidelines to reduce symptoms and avoid using too many drugs. Researchers will compare this approach to usual care in 187 patients living in hospitals or long-term care facilities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Integrated Care Pathway (ICP) combining behavioral activities and medication guidelines
What this could lead to: If successful, this could provide a standardized, effective approach to manage agitation and aggression in Alzheimer's, reducing reliance on multiple medications.
What could go wrong: This is a relatively small study (187 participants) and the intervention is complex, making it hard to isolate which part works. Results may not apply to all care settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aggression Alzheimer disease dementia Psychomotor Agitation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGGRESSION ALZHEIMER DEMENTIA (AD) ALZHEIMER'S DISEASE

Contacts and locations

Locations

Centre for Addiction and Mental Health

Toronto, Ontario, M6J 1H4, Canada
Douglas Hospital Research Centre

Montreal, Quebec, H4H 1R3, Canada
LAWSON Health Research Institute

London, Ontario, N6C 2R5, Canada
Ontario Shores Centre for Mental Health Sciences

Whitby, Ontario, L1N 5S9, Canada
Providence Care

Kingston, Ontario, K7L 4X3, Canada
University of Calgary

Calgary, Alberta, T2N 1N4, Canada

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