New care pathway aims to tame agitation in Alzheimer's without overmedicating

NCT ID NCT03672201

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a structured care pathway for treating agitation and aggression in people with Alzheimer's disease. The pathway combines personalized activities with medication guidelines to reduce symptoms and avoid using too many drugs. Researchers will compare this approach to usual care in 187 patients living in hospitals or long-term care facilities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Integrated Care Pathway (ICP) combining behavioral activities and medication guidelines

What this could lead to

If successful, this could provide a standardized, effective approach to manage agitation and aggression in Alzheimer's, reducing reliance on multiple medications.

What could go wrong

This is a relatively small study (187 participants) and the intervention is complex, making it hard to isolate which part works. Results may not apply to all care settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aggression Alzheimer disease dementia Psychomotor Agitation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    Toronto, Ontario, M6J 1H4, Canada

  • Douglas Hospital Research Centre

    Montreal, Quebec, H4H 1R3, Canada

  • LAWSON Health Research Institute

    London, Ontario, N6C 2R5, Canada

  • Ontario Shores Centre for Mental Health Sciences

    Whitby, Ontario, L1N 5S9, Canada

  • Providence Care

    Kingston, Ontario, K7L 4X3, Canada

  • University of Calgary

    Calgary, Alberta, T2N 1N4, Canada