AGGRESSION

This study tests whether propranolol, a common blood pressure medication, can reduce aggression, self-injury, and severe disruptive behaviors in autistic adolescents and adults. Sixty participants will receive either propranolol or a placebo for 12 weeks, with the option to take …

This study tests a stepped care approach for children aged 8-16 who struggle with anger, defiance, or aggression. All families start with a brief online parenting program. If more help is needed, they are randomly assigned to additional options, including virtual reality-assisted…

This global study tests whether applying a sunlight-reflecting coating to roofs can lower indoor temperatures and improve health. Researchers will enroll 3,200 households in five hot cities across Africa, Asia, Latin America, and the Pacific. They will measure heart rate, blood s…

This study tests whether a virtual reality mindfulness app can help people with schizophrenia or schizoaffective disorder control impulsive aggression. About 58 participants will use the VR app or do distraction tasks, and have their brain activity measured with fMRI. The goal is…

This study tests a short, 3-session program called MERA (Manage Emotions to Reduce Aggression) for veterans with PTSD who struggle with impulsive aggression. The program teaches skills to manage emotions better, with the goal of reducing aggressive outbursts and preparing veteran…

This study tests whether IGC-AD1, a THC-based oral medication, can safely reduce agitation in people with mild to severe Alzheimer's dementia. About 164 participants will receive either the drug or a placebo twice daily for several weeks. Researchers will measure changes in agita…

This study tests a manualized behavioral therapy called Functional Communication Training (FCT) for children aged 3-17 with severe challenging behaviors like aggression and self-injury. The therapy teaches children to communicate their needs instead of acting out. Researchers wil…

This study tests a behavioral program called 'Wise Intervention' designed to reduce aggressive behaviors and promote kindness toward LGB-TNB (lesbian, gay, bisexual, transgender, and non-binary) individuals. The program involves reading scientific studies and personal testimonial…

This study tests a behavioral therapy for children aged 3 to 17 who have frequent problem behavior like aggression or self-injury. The therapy uses a schedule where children sometimes get what they want and sometimes don't, to teach them that the alternative behavior works but no…

This study tests a new treatment for anger and aggression caused by past betrayal during military service. It will include 40 active duty service members and veterans. Participants will complete 14 treatment modules twice a week and fill out surveys before, during, and after the …

This study tests whether adding virtual reality (VR) to a standard anger management program helps young offenders (ages 12-18) reduce aggressive behavior more than the program alone or usual care. Participants attend four weekly sessions, wear a chest band and brain-activity head…

This study tests whether adding visual signals and gradually introducing real-life materials can help children with severe aggression or self-injury maintain progress after communication training. The 24 participants, ages 3 to 17, will be observed in different settings to see if…

This study looks at a common problem in behavior therapy for children with severe aggression or self-injury: sometimes, when therapists stop rewarding problem behaviors (called extinction), the child's behavior briefly gets worse before improving. This 'extinction burst' can be d…

This study tests whether cognitive remediation—brain exercises with coaching—can improve thinking skills and reduce aggression in 30 forensic inpatients with conditions like psychosis, ADHD, or substance use. Participants will do exercises and be compared to an active control gro…