RECTAL ADENOCARCINOMA
Clinical trials for RECTAL ADENOCARCINOMA explained in plain language.
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New drug combo tested to shrink rectal tumors before surgery
Disease control OngoingThis early-stage study aims to find the safest dose of the chemotherapy drug TAS-102 when given alongside radiation therapy to patients with stage II or III rectal cancer. The goal is to shrink the tumor before the patient undergoes standard surgery and follow-up chemotherapy. Re…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Doctors test Real-Time MRI scans to boost rectal cancer treatment
Disease control OngoingThis early-phase study is testing whether using MRI scans to guide and adjust radiation therapy in real-time is a practical approach for treating rectal cancer. It involves 20 adults with locally advanced rectal adenocarcinoma who have not had prior pelvic radiation. The main goa…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug duo tested for Tough-to-Treat colon cancer
Disease control OngoingThis study is testing whether a combination of two drugs, cabozantinib and nivolumab, can help control advanced colorectal cancer that has stopped responding to standard treatments. It will involve about 48 adults whose cancer has spread and is a specific type called microsatelli…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Tracking life after rectal cancer: how surgery affects daily living
Knowledge-focused TerminatedThis study aims to understand how rectal cancer surgery affects patients' quality of life over time. Researchers will follow 430 patients for up to 5 years after their surgery, asking them to complete questionnaires about their daily experiences. The goal is to gather information…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists hunt genetic clues to rising colon cancer in young adults
Knowledge-focused OngoingThis study aims to understand why colorectal cancer is increasingly affecting younger adults by comparing genetic and lifestyle factors between patients diagnosed before age 50 and those diagnosed later. Researchers will analyze DNA from 818 patients and their family members to i…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC