New combo therapy aims to save rectums from surgery

NCT ID NCT06417476

First seen Apr 16, 2026 · Last updated May 02, 2026 · Updated 2 times

Summary

This study tests two types of radiation (short or long course) followed by a strong chemotherapy combo (mFOLFOXIRI) in people with low rectal cancer. The goal is to shrink the tumor enough to avoid major surgery and keep the rectum working normally. About 66 adults with stage T2-4a rectal cancer will take part to see if this approach can safely preserve the organ.

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Contacts and locations

Locations

  • 651 Dongfeng Road East

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.