New rectal cancer device tested in elderly patients

NCT ID NCT04336202

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a new rectal applicator for delivering radiation therapy to elderly patients with inoperable rectal cancer. The treatment combines external beam radiation with three sessions of internal radiation (brachytherapy) using the new device. The study aims to see if the new applicator is safe, feasible, and effective at shrinking tumors, while monitoring for side effects like rectal bleeding or diarrhea.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
External beam radiotherapy and endorectal brachytherapy with a new rectal applicator
What this could lead to
If successful, this new applicator could offer a safer, more effective radiation treatment option for elderly patients with inoperable rectal cancer, potentially improving quality of life and tumor control.
What could go wrong
This is a small, early pilot study with only 45 participants and is currently suspended. The new device may not work better than existing ones, and there is a risk of severe side effects like rectal bleeding or diarrhea.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

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