RECTAL ADENOCARCINOMA
Clinical trials for RECTAL ADENOCARCINOMA explained in plain language.
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Shrinking tumors smarter: MRI-Guided combo aims to cut side effects in rectal cancer
Disease control Not yet recruitingThis study tests a new approach for people with locally advanced rectal cancer. Before surgery, patients receive a shorter, MRI-guided radiation treatment combined with immunotherapy and chemotherapy. The goal is to shrink the tumor more effectively while reducing side effects fr…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Longhao Li • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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Powerful new cocktail aims to beat back aggressive rectal cancer
Disease control Not yet recruitingThis study tests whether adding a targeted therapy (cetuximab or bevacizumab) and an immunotherapy drug (PD-1 antibody) to standard short-course radiation and chemotherapy can better control high-risk rectal cancer that is not caused by certain gene faults. About 204 adults with …
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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New combo therapy aims to shrink rectal tumors without surgery
Disease control Not yet recruitingThis study tests a mix of four treatments—immunotherapy, a cancer-killing virus, short radiation, and chemotherapy—given before any surgery for people with locally advanced rectal cancer. The goal is to see if this combination can make the tumor disappear completely and avoid the…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Chongqing University Cancer Hospital • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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Hidden cancer clues: are doctors missing key tumor deposits?
Knowledge-focused Not yet recruitingThis study checks whether doctors are now properly reporting small cancer spots called tumor deposits in rectal cancer patients. These deposits can signal a higher risk of cancer returning, but they were often missed under older reporting rules. By comparing reports before and af…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated May 17, 2026 02:14 UTC
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Who should tell relatives about cancer genes? study tests doctor vs. patient approach
Knowledge-focused Not yet recruitingThis study looks at the best way to inform close relatives (parents, siblings, children) of people newly diagnosed with colorectal cancer about their possible genetic risk. Some families will have a doctor or healthcare provider reach out to relatives directly, while others will …
Matched conditions: RECTAL ADENOCARCINOMA
Phase: NA • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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New camera could cut waiting lists for rectal cancer checks
Knowledge-focused Not yet recruitingThis study tests a new short camera (rectoscope) to check for regrowth after rectal tumor removal. It aims to see if using this camera with a simple enema instead of strong bowel medicine can be done safely in the clinic, reducing waiting lists. The study will include 30 adults w…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Blood test may spare rectal cancer patients from unnecessary surgery
Knowledge-focused Not yet recruitingThis study tests whether a sensitive blood test (ctDNA) can help doctors decide the best treatment for people with early-stage rectal cancer. About 200 adults will be enrolled to see if using the blood test leads to better outcomes, like complete tumor disappearance or longer sur…
Matched conditions: RECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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New study explores less invasive options for rectal cancer treatment
Knowledge-focused Not yet recruitingThis study looks at how newer, less invasive endoscopic techniques compare to standard surgery for treating early rectal tumors. Researchers will review medical records from 300 adults treated between 2015 and 2025 to see if these methods are safer and just as effective. The goal…
Matched conditions: RECTAL ADENOCARCINOMA
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC