New Stitch-Free staple technique aims to cut leak risk in rectal cancer surgery

NCT ID NCT07376980

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a modified stapling technique (MST) against the standard method in 450 adults having minimally invasive rectal cancer surgery. The goal is to see if MST reduces the chance of anastomotic leaks, a serious complication. Participants will be randomly assigned to one of the two techniques and monitored for leaks within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

modified single-stapled anastomosis (a surgical technique)

What this could lead to

If successful, this new stapling method could lower the risk of dangerous leaks after rectal cancer surgery, leading to safer recovery.

What could go wrong

This is a surgical technique study, not a new drug. Results may show no significant benefit over the standard method, and individual surgeon skill can affect outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Kyung Hee University Hospital

    Seoul, 02447, South Korea

  • Kyungpook National University Chilgok Hospital

    Daegu, Gyeongsangbuk-do, 41404, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital

    Seoul, 03722, South Korea

  • St. Vincent's Hospital

    Suwon, Gyeonggi-do, 16247, South Korea