New Stitch-Free staple technique aims to cut leak risk in rectal cancer surgery

NCT ID NCT07376980

ENROLLING_BY_INVITATION Disease control Sponsor: Korea University Anam Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a modified stapling technique (MST) against the standard method in 450 adults having minimally invasive rectal cancer surgery. The goal is to see if MST reduces the chance of anastomotic leaks, a serious complication. Participants will be randomly assigned to one of the two techniques and monitored for leaks within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: modified single-stapled anastomosis (a surgical technique)
What this could lead to: If successful, this new stapling method could lower the risk of dangerous leaks after rectal cancer surgery, leading to safer recovery.
What could go wrong: This is a surgical technique study, not a new drug. Results may show no significant benefit over the standard method, and individual surgeon skill can affect outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER RECTAL CANCER SURGERY RECTAL NEOPLASMS RECTAL NEOPLASMS MALIGNANT

Contacts and locations

Locations

Korea University Anam Hospital

Seoul, 02841, South Korea
Kyung Hee University Hospital

Seoul, 02447, South Korea
Kyungpook National University Chilgok Hospital

Daegu, Gyeongsangbuk-do, 41404, South Korea
Seoul National University Hospital

Seoul, 03080, South Korea
Severance Hospital

Seoul, 03722, South Korea
St. Vincent's Hospital

Suwon, Gyeonggi-do, 16247, South Korea

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