POSTOPERATIVE DELIRIUM

This trial compares two anesthesia drugs—remimazolam and propofol—to see which one leads to less postoperative delirium (sudden confusion) in people undergoing brain surgery. Delirium is a common complication that can slow recovery. The study involves about 700 neurosurgery patie…

This study tested whether using a device to stimulate the diaphragm (the main breathing muscle) during brain surgery could lower the risk of postoperative problems like confusion (delirium) and lung issues. Researchers enrolled 120 adults undergoing brain tumor removal. Half rece…

This study tested if being in a room with natural light instead of artificial light could prevent delirium (sudden confusion) after heart surgery. Researchers observed 448 adults in the ICU. The goal was to see if natural light lowers the chance of delirium and reduces the need f…

This study tested whether giving electroacupuncture 30 minutes before major surgery could lower the chance of postoperative delirium (sudden confusion) in patients aged 65 to 90. Over 1,100 participants were randomly assigned to receive real or sham acupuncture. The goal was to s…

This study looked at 50 adults having heart bypass surgery to see if one sedative (dexmedetomidine) causes less confusion after surgery than another (midazolam). The goal was to find a way to reduce postoperative delirium, a common problem after heart surgery. Researchers checked…

This study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…

This study tested whether transcutaneous electrical acupoint stimulation (TEAS) — a mild electrical pulse on specific acupoints — could reduce postoperative delirium (confusion) in 226 elderly patients having abdominal surgery. Researchers also looked at brain wave (EEG) changes …

This study compared two methods of pain control for people having back fusion surgery: a nerve block given before surgery versus numbing medicine injected at the end. Researchers measured pain, inflammation, confusion after surgery, and overall recovery in 29 adults. The goal is …

This study tested whether adding a second nerve block to a standard one can better control pain after heart surgery. Forty-two adults having elective heart surgery through a breastbone incision received either one or two nerve blocks. The goal was to see if the combination reduce…

This study tested whether using EEG brain-wave monitoring during general anesthesia could reduce postoperative delirium and pain in children aged 4-10 having dental surgery. 92 children were randomly assigned to receive either standard anesthesia care or EEG-guided care. Research…

This study tested a combination of brain monitoring and specific drugs during heart surgery to see if it could reduce confusion, pain, and blood pressure problems afterward. 70 older adults (60+) having heart bypass or valve surgery took part. The approach used EEG monitoring and…

This study tested whether the sleep medication suvorexant (Belsomra) can help older adults sleep better and reduce confusion after heart surgery. One hundred patients aged 60 and older received either suvorexant or a placebo for seven nights in the ICU. Researchers measured sleep…

This study followed 610 adults who had heart surgery to see how often they develop postoperative delirium—a sudden state of confusion that can come and go. Researchers collected information on known risk factors like age, high blood pressure, and diabetes, and tracked outcomes su…

This study compared two common sedation drugs, propofol and dexmedetomidine, in 65 older adults undergoing a less invasive heart valve replacement called TAVR. The goal was to see which drug leads to better kidney function, less confusion, and fewer complications after the proced…

This study looked at how often patients develop confusion after surgery (postoperative delirium) and what factors increase the risk. Researchers tracked over 2,400 adults in Spanish hospitals who had surgery requiring an overnight stay. The goal is to use this information to crea…

This study looked at whether two substances in the blood, zonulin and interleukin-8, are linked to delirium (sudden confusion) after hip fracture surgery in older adults. Researchers measured these markers before and after surgery in 73 patients over 65. The goal was to see if th…