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Blood test may predict delirium risk after hip surgery in seniors

NCT ID NCT04875182

Knowledge-focused Sponsor: Dr. Gokhan Vural Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether two substances in the blood, zonulin and interleukin-8, are linked to delirium (sudden confusion) after hip fracture surgery in older adults. Researchers measured these markers before and after surgery in 73 patients over 65. The goal was to see if these markers could help predict who might develop delirium, but this was an observational study, not a treatment trial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify patients at risk for delirium after hip surgery, allowing for earlier monitoring or prevention.
What could go wrong
This is a small, completed observational study. It only looks for a link between blood markers and delirium, not a treatment. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

73 people

The number who actually took part.

Started

May 2021

Finished

Sep 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Both male and female patients over 65 years of age who will undergo femur neck and inthertrocanteric fracture surgery with regional anesthesia

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients over 65 years with mini mental state score \> 21, undergoing femur fixation surgery Exclusion Criteria: * anticholinergic drug use, known epilepsy, Parkinson, Alzheimer's disease, dementia, cognitive function disorder

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Conditions

The condition(s) this trial relates to.

Emergence Delirium femoral neck fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative delirium

Contacts and locations

Locations

  • Muğla Sıtkı Koçman University

    Muğla, Menteşe, 48000, Turkey (Türkiye)

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