POSTOPERATIVE COMPLICATIONS

This study looks at whether giving patients with bone or soft tissue sarcoma a special nutritional supplement twice daily before surgery can reduce complications and help maintain muscle mass. About 100 adults scheduled for tumor removal will be randomly assigned to receive eithe…

This study compares two types of stitches used to close the vaginal cuff after laparoscopic hysterectomy in women with gynecologic cancers. The goal is to see if a newer self-locking stitch reduces complications like wound opening, infection, or bleeding within three months after…

This study is testing a new surgical stapler (Signia™) used to reconnect the colon after part of it is removed. The main goal is to see how often leaks happen at the connection site. About 137 adults having planned left-sided colon or rectal surgery will take part.

This study looks at whether adding a protein called albumin to the standard IV fluids given during a major cancer surgery (cytoreduction with heated chemotherapy) can lower the risk of complications after the operation. About 140 adults with peritoneal cancer will be randomly ass…

This study looks at whether using a reinforcement patch on the stapler during stomach cancer surgery can lower the chance of complications like leaks or narrowing at the connection site. About 382 adults with stomach cancer will be randomly assigned to get either the standard sta…

This study looks at whether a remote expert can guide a bedside ultrasound to find fluid buildup in the belly after liver surgery. About 40 patients will be scanned within 72 hours of their operation. The goal is to see if this remote method is as accurate as a standard ultrasoun…

This study tests a new, dye-free way to check blood flow during gastrointestinal surgery. About 200 adults having planned gut surgery will be randomly assigned to either the new light-based method (iPPG) or the standard dye method (ICG). The goal is to see if the new method works…

This study compares four mouthwashes—Bone Bioactive Liquid, Hyaluronic Acid, Chlorhexidine, and Warm Saline—to see which one helps gums heal best after wisdom tooth removal. About 100 adults with an impacted lower wisdom tooth will use one of the rinses and be checked for healing…

This study tests whether helping people sleep better for four weeks before knee or hip replacement surgery can reduce pain and speed up recovery afterward. One hundred adults with insomnia symptoms will receive either a brief sleep therapy or sleep education before their operatio…

This study tests whether a special vacuum bandage (negative pressure wound therapy) can prevent infections better than standard dressings after skin grafts on the lower leg. About 242 adults who have a skin tumor removed and need a skin graft will take part. The bandage is applie…

This study tests a simple idea: having a parent or family member involved in a child's anesthesia care to reduce emergency delirium—a state of confusion, crying, or thrashing when waking up from surgery. Researchers will compare this family-centered approach to standard care in 4…

This study compares two ways to give breathing exercises to people with non-small cell lung cancer before and after lung surgery. Half of the 560 participants will use a smartphone app called Fissios along with in-person physiotherapy sessions, while the other half will only atte…

This study compares three breathing treatments (IPPB, EzPAP, and Metaneb) to see which one helps lungs expand and recover best after heart surgery. About 324 adults who had coronary bypass or valve surgery will take part. The goal is to find the most effective therapy to improve …

This study looks at whether fun breathing exercises, like blowing balls or bubbles, can help children aged 3 to 7 feel less anxious before surgery and recover more smoothly afterward. About 80 kids will be split into two groups: one does the breathing games, the other gets standa…

This study tests whether a structured nurse-led education session and direct referral to pelvic floor physiotherapy before prostate removal surgery can reduce urine leakage afterward. About 80 men scheduled for prostate cancer surgery will be randomly assigned to either standard …

This study tests whether a smartphone app that tracks symptoms can help lung cancer patients do their prescribed rehabilitation exercises after minimally invasive surgery. About 736 patients will use the app, with some getting extra feedback from their care team. The goal is to s…

This study tests whether tea tree oil mouthwash works as well as chlorhexidine mouthwash for reducing pain, swelling, and jaw stiffness after having a wisdom tooth removed. About 54 adults will use one of the two mouthwashes three times a day for a week. Researchers will measure …

This study is a registry that will collect information from 8,000 people having heart or chest surgery. The goal is to find out which factors before and during surgery are linked to serious problems like death, shock, or needing another surgery. The results may help doctors impro…

This study is observing 42 adults who are admitted to the intensive care unit (ICU) after surgery. Researchers want to see if levels of a substance called IL-6 and other inflammation markers in the blood can help predict which patients are at higher risk of dying or having seriou…

This study looks at whether showering with surgical drains in place after breast reduction or tummy tuck surgery leads to more infections or other problems. About 100 adults will be randomly assigned to either shower or not shower while they have drains. The goal is to help docto…

This study is testing a new AI tool called DeepComp that uses CT scans to predict which stomach cancer patients are at high risk for serious complications after surgery. Researchers will enroll 500 patients across five medical centers and compare the AI's predictions with what ac…

This study looks at adults having dental procedures under general anesthesia to see if undiagnosed sleep apnea raises the risk of breathing problems after surgery. Researchers will use two common screening tools (STOP-BANG and ASA criteria) to identify high-risk patients and refe…

This study is testing whether a special nutrition shake given after surgery can help older adults (70+) regain physical and mental function faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half will follow standard recovery advice. Th…

This study reviews 10 years of medical records from 600 adults who had thyroid surgery at Minia University Hospital. The goal is to find out which patients are most likely to develop low calcium levels after surgery, a common complication. By identifying key risk factors, doctors…

This study looks at different scoring systems to see which best predicts whether a person will need intensive care after cancer surgery. Researchers will follow 500 adults having cancer surgery and compare the accuracy of these tools. The goal is to help doctors plan better and u…

This study follows 30 women having DIEP flap breast reconstruction after mastectomy. Researchers will measure inflammation and stress markers in blood samples taken before and after surgery. The goal is to learn how the body heals and what affects recovery, which may help improve…

This study is creating a tool to predict heart injury in patients having major liver surgery. Researchers will collect data from 1,800 adults to build a model that uses patient health, surgery details, and blood tests. The goal is to help doctors identify high-risk patients and p…

This study is checking if a blood test called phosphatidylethanol (PEth), which shows how much alcohol someone has had in the past few weeks, can help predict problems after surgery. Researchers will test 170 adults who drink alcohol and are having surgery that requires a hospita…

This study looks at whether a special heart ultrasound done before cardiovascular surgery can help predict if a patient will develop atrial fibrillation (an irregular heartbeat) after the operation. Researchers will follow 138 adults who are in normal rhythm before surgery and ch…

This study tests a new way to give fluids during abdominal surgery. Doctors will use breathing-related changes in a neck vein to decide how much fluid to give. The goal is to see if this method reduces complications like infections, heart issues, or kidney problems after surgery.…

This study is watching 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like confusion (delirium). Researchers will collect blood samples and health information to build a tool that predicts these risks. The goal is to better understa…

This study compares two types of staplers (linear vs circular) used to reconnect the esophagus to the small intestine after stomach removal surgery for gastric cancer. Researchers want to see which stapler leads to fewer complications and shorter surgery time. About 100 adults wi…

This study aims to find out if certain substances in the blood can help predict serious complications after high-risk surgeries like heart, lung, or colon operations. Researchers will collect blood samples from about 5,000 patients before and after surgery and track their recover…

This study observes 10,000 adults worldwide who need a breathing machine during surgery. Researchers will track lung problems after surgery and how the machine is used. The goal is to find ways to make surgery safer for everyone.

This study is looking for ways to predict postoperative delirium—a state of confusion that can happen after surgery in older adults. Researchers will measure certain substances in the blood of 1,170 patients aged 65 and older before and after major surgery. They hope to find a re…

This study will see if an artificial intelligence (AI) model can predict major heart problems within 30 days after gastrointestinal surgery better than current risk scores. Researchers will review medical records of 5,000 adults having surgery at Bach Mai Hospital in 2025-2026. T…

This study looks at whether taking out the breathing tube in the recovery room instead of the operating room after robot-assisted surgery can free up the OR faster. About 218 adults having elective robot-assisted laparoscopic surgery will be randomly assigned to one of two groups…

This study will use artificial intelligence to predict complications in children who have a common heart defect repaired with a catheter procedure. Researchers will analyze data from over 5,000 children, including lab results, heart images, and medical records, to build a model t…

This study looks at infections that happen after surgery to remove esophageal cancer. Researchers will review medical records of 350 adults who had this surgery in France between 2017 and 2024. The goal is to find out how common these infections are, what causes them, and how the…