PERCUTANEOUS CORONARY INTERVENTION
Clinical trials for PERCUTANEOUS CORONARY INTERVENTION explained in plain language.
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Twice-Yearly shot aims to cut heart attacks and amputations
Disease control Recruiting nowThis study tests whether inclisiran, a twice-yearly injection that lowers cholesterol, can prevent major heart and limb events in 6,000 people who recently had artery-opening procedures. Participants receive either inclisiran or a placebo shot at the start, at 90 days, and every …
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated Jul 02, 2026 04:00 UTC
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New stomach drug could shield heart patients from bleeding
Disease control Recruiting nowThis study compares two stomach-acid-lowering drugs—tegoprazan and rabeprazole—in about 3,300 heart disease patients who take blood thinners and are at high risk for stomach bleeding. The goal is to see if tegoprazan works as well as rabeprazole at preventing serious gut problems…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: PHASE4 • Sponsor: Duk-Woo Park, MD • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Timing of blood thinner injection could prevent artery blockage after heart procedure
Disease control Recruiting nowThis study is testing whether giving the blood thinner heparin before inserting a tube into the wrist artery can prevent a common complication: blockage of that artery. About 550 people undergoing a heart procedure through the wrist will be randomly assigned to receive heparin ei…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Heart stent patients: could a tailored blood thinner dose prevent clots and bleeding?
Disease control Recruiting nowThis study looks for the best type and dose of blood thinner (P2Y12 inhibitor) for people who have had a heart stent placed. After an initial period on two blood thinners, patients switch to one. The goal is to find a dose that keeps blood clotting at a safe level—not too high (w…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: PHASE3 • Sponsor: Cardiocentro Ticino • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Simple cuff trick may shield heart failure patients from kidney damage
Disease control Recruiting nowThis study tests whether briefly inflating a blood pressure cuff on the arm before a heart procedure can protect the kidneys and heart in people with congestive heart failure. About 240 participants will be randomly assigned to receive either the real cuff inflations or a sham ve…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: PHASE2, PHASE3 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Heart artery balloon showdown: which works better for Medium-Small vessels?
Disease control Recruiting nowThis study compares two types of drug-coated balloons (Selution sirolimus vs. SeQuent Please Neo paclitaxel) to treat narrowed coronary arteries in medium-small vessels. About 140 adults with stable angina or stabilized acute coronary syndrome will be enrolled. The main goal is t…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can a natural compound help heart patients on blood thinners?
Disease control Recruiting nowThis study tests whether adding berberine, a natural compound, can improve blood thinning in heart patients who already take aspirin and clopidogrel after a stent procedure. About 64 adults will receive either standard treatment or berberine at increasing doses for 12 weeks. The …
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: PHASE4 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Heart patients may get kidney shield from diabetes pills
Disease control Recruiting nowThis study looks at whether SGLT2 inhibitors (drugs like empagliflozin and dapagliflozin, typically used for diabetes) can prevent acute kidney injury caused by contrast dye used in heart X-rays and stent procedures. Researchers will review records of 4,000 patients who had these…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: Collegium Medicum w Bydgoszczy • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Smart algorithm aims to tailor blood thinner use after stents
Disease control Recruiting nowThis study tests whether a risk-score algorithm can safely personalize how long patients take dual antiplatelet therapy (two blood thinners) after getting a heart stent. About 2,788 participants will be assigned to either algorithm-guided or standard treatment duration. The goal …
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Disease control
Last updated Jun 26, 2026 17:59 UTC
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New heart pump aims to make risky angioplasty safer
Disease control Recruiting nowThis study tests a temporary heart pump called iVAC 2L in 100 patients undergoing high-risk angioplasty. The pump helps stabilize blood flow during the procedure. Researchers will track deaths, heart attacks, strokes, and other complications for up to a year to see if the device …
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Disease control
Last updated Jun 26, 2026 14:34 UTC
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New heart test could replace painful procedure – no extra wires needed!
Diagnosis Recruiting nowThis study tests a new technology called IVUS-FFR that uses ultrasound images from inside heart arteries to quickly check if a blockage is serious enough to need a stent. Unlike the current standard test, it doesn't require an extra pressure wire or medication that can cause disc…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: China National Center for Cardiovascular Diseases • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC
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Groin pain during heart procedures? nerve block may offer relief
Symptom relief Recruiting nowThis study tests whether a numbing injection (TAP block) given before heart procedures done through the groin can reduce pain and improve patient and doctor satisfaction. About 100 adults having planned heart catheterization or stent placement will be randomly assigned to receive…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can we predict how long heart patients must lie still after a procedure?
Knowledge-focused Recruiting nowThis study is observing ICU heart patients who have a femoral artery sheath removed after procedures like cardiac catheterization. Researchers want to find out what factors affect how long it takes for bleeding to stop and how long patients must lie flat. The goal is to create a …
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Heart patients and doctors rank what matters most in clinical trials
Knowledge-focused Recruiting nowThis study asks 600 people—heart disease patients and healthcare providers—to rate how serious different complications are, like heart attack or stroke, compared to death. The goal is to better understand if patients and doctors value these events differently. The results could h…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: Xijing Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Heart patients and doctors weigh in: stent or no stent?
Knowledge-focused Recruiting nowThis study looks at what heart disease patients and their doctors prefer when choosing between two treatments: a permanent metal stent or a drug-coated balloon that dissolves over time. Researchers want to understand how much extra risk people are willing to accept to avoid havin…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: Xijing Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Poland launches massive heart registry to improve artery clearing techniques
Knowledge-focused Recruiting nowThis observational study will follow 1,000 patients in Poland who undergo a procedure to open completely blocked heart arteries. Researchers will collect data on success rates, complications, and long-term outcomes to understand what works best in everyday practice. The goal is t…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: National Institute of Cardiology, Warsaw, Poland • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Massive new registry aims to unlock Heart-Kidney mysteries
Knowledge-focused Recruiting nowThis study is a large registry that will collect health information from up to 60,000 people with both heart and kidney disease. The goal is to better understand how these conditions interact and to find ways to predict and improve patient outcomes. No new treatments or procedure…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Heart artery showdown: which technique wins?
Knowledge-focused Recruiting nowThis study compares two methods for opening completely blocked heart arteries: antegrade dissection and re-entry (ADR) versus a retrograde approach. Researchers will measure procedure time, success rates, complications, and even doctor stress levels. 74 participants with difficul…
Matched conditions: PERCUTANEOUS CORONARY INTERVENTION
Phase: NA • Sponsor: National Institute of Cardiology, Warsaw, Poland • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC