Heart stent patients: could a tailored blood thinner dose prevent clots and bleeding?

NCT ID NCT07582835

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks for the best type and dose of blood thinner (P2Y12 inhibitor) for people who have had a heart stent placed. After an initial period on two blood thinners, patients switch to one. The goal is to find a dose that keeps blood clotting at a safe level—not too high (which could cause a heart attack) and not too low (which could cause bleeding). The trial will test reduced doses of ticagrelor and prasugrel against standard clopidogrel in 355 adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clopidogrel, ticagrelor, prasugrel (antiplatelet drugs)

What this could lead to

If successful, this could help doctors choose the best drug and dose for long-term heart patients, reducing both heart attacks and dangerous bleeding.

What could go wrong

This is a single-center study with only 355 participants, so results may not apply to everyone. The optimal dose found may still not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Istituto Cardiocentro Ticino

    RECRUITING

    Lugano, Ch/ti, 6900, Switzerland

    Contact Email: •••••@•••••