Which blood pressure combo works best after a heart stent?

NCT ID NCT07683585

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial compares two different dual blood pressure medications in people aged 50–70 with high blood pressure and heart disease who have just received a heart stent. Participants are randomly assigned to one of two drug combinations: losartan plus hydrochlorothiazide or amlodipine plus azilsartan. The study measures how well each combination lowers blood pressure, affects chest pain, and impacts daily life over 12 weeks after leaving the hospital.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Losartan + Hydrochlorothiazide and Amlodipine + Azilsartan
What this could lead to
If one combination works better, it could improve blood pressure control and quality of life for people who have had a heart stent.
What could go wrong
This is a small, early-stage study, so results may not apply to everyone. Both treatments are already approved, so no major new breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Medical Research Center for Therapy and Preventive Medicine

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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