PANCREATIC DUCTAL ADENOCARCINOMA

This study tested whether adding two immunotherapy drugs (nivolumab and BMS-813160) with or without a cancer vaccine (GVAX) could help control locally advanced pancreatic cancer after standard chemotherapy and radiation. Researchers enrolled 46 patients to check if this combinati…

This study tested whether adding an experimental drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe and might work better for people with advanced pancreatic cancer that cannot be removed by surgery. The main goal was to check for side effects in about 43 patients. …

This large, completed study tested whether adding a targeted drug (erlotinib) to standard chemotherapy, or adding radiation therapy after chemotherapy, could help patients live longer after surgery for pancreatic cancer. It involved 546 adults whose pancreatic tumors were surgica…

This early-stage trial tested a new immunotherapy called ELI-002 in 25 people with pancreatic, colorectal, lung, and other cancers that have specific KRAS mutations. The treatment was given after standard therapy to target any remaining cancer cells and prevent recurrence. Resear…

This study tested whether adding one or two experimental immunotherapy drugs to standard chemotherapy, given both before and after surgery, could better control high-risk pancreatic cancer. It involved 28 adults with surgically removable pancreatic cancer who had not received pri…

This study tested a two-step treatment for advanced pancreatic cancer. First, patients received standard chemotherapy plus experimental drugs designed to make cancer cells more vulnerable. If their disease was controlled after three cycles, they moved to a second phase receiving …

This study tested whether adding a new oral drug called onvansertib to a standard chemotherapy combination could help control metastatic pancreatic cancer after the first treatment stopped working. It involved 41 adults whose cancer had spread and who had already tried one prior …

This study compared two standard chemotherapy treatments for people with newly diagnosed, advanced pancreatic cancer that has spread. Researchers tested whether they could use tumor samples and lab tests to predict which treatment would work better for each patient. The goal was …

This study tested a new type of PET scan designed to better detect and locate gastrointestinal cancers. The scan uses a special tracer that attaches to a protein often found in these tumors. Researchers compared the scan results to tissue samples from 109 patients to see how accu…

This study tested a new type of PET scan designed to see pancreatic cancer in a new way. The goal was to see if this scan could help doctors predict which patients would respond to standard chemotherapy or to a newer type of targeted therapy. The trial involved 69 adults with pan…