Could a new PET scan help match pancreatic cancer patients to the right therapy?
NCT ID NCT03851237
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 1 trial tested a new radioactive imaging agent called 64Cu-DOTA-ECL1i to see if it can detect a protein called CCR2 in pancreatic tumors using PET scans. The study involved 69 adults with pancreatic ductal adenocarcinoma at various stages. The goal was to see if the scan could predict how well patients would respond to standard chemotherapy or a CCR2-targeted therapy, potentially helping doctors choose the best treatment for each patient.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 64Cu-DOTA-ECL1i (a radioactive imaging agent)
- What this could lead to
- If successful, this imaging test could help doctors identify which pancreatic cancer patients are likely to respond to CCR2-targeted therapy, avoiding ineffective treatments.
- What could go wrong
- This is an early phase 1 study with only 69 participants, so the imaging agent may not reliably predict treatment response in larger, more diverse groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Washington University School of Medicine
St Louis, Missouri, 63110, United States
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