OVERWEIGHT

This study is testing whether adding extra virgin olive oil to a Mediterranean diet can help people with fatty liver disease (MASLD). Researchers will compare the effects of a standard amount (3 tablespoons) to a higher amount (9 tablespoons) daily over about 10 weeks. They will …

This is an early-stage study to test the safety and effects of a new injectable drug called brenipatide in healthy adults who are overweight or have obesity. Researchers will give different doses to about 150 participants to see how the body handles the drug and if it helps reduc…

This study is testing a 9-month support program to help new mothers improve their heart health after a first pregnancy complicated by preeclampsia. The program uses a special smartphone app for tracking blood pressure and weight, along with online coaching and group meetings. Res…

This study aims to find the most effective combination of four dietary strategies for weight loss in a fully digital program. Researchers will enroll 208 U.S. adults with overweight or obesity in a 12-week remote program testing different approaches to eating. The goal is to iden…

This study aims to see if two different injection devices for the weight loss medication CagriSema work the same way. About 1,400 adults with overweight or obesity will be randomly assigned to receive either the medication or a placebo for about one year. The main goal is to comp…

This early-stage study aims to see if combining two new experimental weight-loss drugs causes fewer stomach-related side effects, like nausea and vomiting, than taking just one of the drugs. About 100 adults with overweight or obesity will receive the drug combination in one part…

This study aims to see if a new weekly injection called NNC0487-0111 is safe and works better than the approved drug semaglutide for people with both excess weight and type 2 diabetes. About 1,000 adults will be randomly assigned to receive either the new drug or semaglutide, bot…

This small pilot study is testing a new group program designed to help people with obesity or overweight increase their physical activity in a healthy way. The main goal is to see if the program helps people exercise more without developing unhealthy relationships with food or ex…

This is a very early safety study for a new injection called SHR-2906, which is being developed to help with obesity. The main goal is to see if the drug is safe and how the body processes it. The study will first test single doses in healthy volunteers, then test multiple doses …

This is the first study to give the experimental drug SA030 to people. Researchers want to see if a single injection is safe and how the body handles it in 40 healthy adults who are overweight or obese. The main goal is to check for side effects and understand how the drug moves …

This study aims to check how safe and effective the medication tirzepatide is for adults in India who have type 2 diabetes or who are overweight/obese. About 344 participants will receive the medication for 46 weeks. Researchers will monitor side effects, weight changes, and bloo…

This study is testing whether drinking water with extra hydrogen dissolved in it can help adults with persistent excess weight. Researchers will compare the effects of this special water to regular water in 120 participants across multiple clinics. The goal is to see if it safely…

This VA program aims to help clinics better provide proven health services for women Veterans in midlife. It will test two different support strategies across at least 18 VA facilities to help them offer trauma-informed care, menopause symptom therapy, and weight management progr…