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New weekly shot could help asian adults shed pounds

NCT ID NCT07668401

Not yet recruiting Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This Phase 3 study tests whether a weekly injection called zenagamtide helps Asian adults with overweight or obesity lose weight safely. About 400 participants will receive either the drug or a placebo for several weeks. The main goal is to see how much body weight changes, with waist size also measured.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zenagamtide
What this could lead to
If it works, this could offer a new weekly injection to help Asian adults with overweight or obesity lose weight and reduce waist size.
What could go wrong
This is a Phase 3 trial, but results may not apply to all populations. Side effects from the injection are possible, and the drug may not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY OVERWEIGHT

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Ajou University Hospital_Family Medicine

    Suwon, Gyeonggi-do, 16499, South Korea

  • All India Institute of Medical Science (AIIMS), Guwahati

    Assam, 781101, India

  • All India Institute of Medical Sciences (AIIMS), Nagpur

    Nagpur, Maharashtra, 441108, India

  • BSES MG hospital

    Mumbai, Maharashtra, 400058, India

  • Chellaram Diabetes Institute

    Pune, Maharashtra, 411021, India

  • Christian Medical College Hospital, Vellore

    Vellore, Tamil Nadu, 632004, India

  • Diabetes Research Center, Hyderabad

    Hyderabad, Telangana, 500 082, India

  • Excel Endocrine Centre

    Kolhāpur, Maharashtra, 416008, India

  • Fukuwa Clinic_Internal Medicine

    Tokyo, 104-0031, Japan

  • GMERS Medical college and hospital

    Vadodara, 390021, India

  • Government Medical College, Kozhikode

    Kozhikode, Kerala, 673008, India

  • Grant Medical Foundation Ruby Hall Clinic

    Pune, Maharashtra, 411001, India

  • Hospital Canselor Tuanku Muhriz UKM

    Cheras, Kuala Lumpur, 56000, Malaysia

  • Hospital Melaka

    Malacca, 75400, Malaysia

  • Hospital Miri

    Miri, Sarawak, 98000, Malaysia

  • Hospital Putrajaya

    Putrajaya, 62250, Malaysia

  • Karnataka Medical College and Research Institute

    Hubbali, Karnataka, 580022, India

  • Kindai University Hospital_Department of Endocrinology, Metabolism and Diabetes

    Sakai-shi, Osaka, 590-0197, Japan

  • Konkuk University Medical Center_Endocrinology

    Seoul, 05030, South Korea

  • Kyungpook National University Hospital_Family Medicine

    Daegu, 41944, South Korea

  • Madras Diabetes Research Foundation

    Chennai, Tamil Nadu, 600086, India

  • Maulana Azad Medical College

    Delhi, New Delhi, 110002, India

  • Medical Corporation Shinanokai Shinanozaka Clinic_Internal Medicine

    Shinjuku-ku, Tokyo, 160-0017, Japan

  • Nirmal Hospital Pvt. Ltd.

    Surat, Gujarat, 395002, India

  • OCROM Clinic_Internal medicine

    Suita-shi, Osaka, 565-0853, Japan

  • Osmania General Hospital

    Hyderabad, Telangana, 500012, India

  • Pusan National University Yangsan Hospital_Family Medicine

    Yangsan, Gyeongsangnam-do, 50612, South Korea

  • Ramathibodi Hospital

    Bangkok, 10400, Thailand

  • SMS Hospital

    Jaipur, 302004, India

  • SSG Hospital, Baroda

    Vadodara, Gujarat, 390001, India

  • Seoul National University Bundang Hospital_Endocrinology

    Seoungnam-si, Gyeonggi-do, 13620, South Korea

  • Shalini Tai Meghe Hospital and Research Center

    Nagpur, Maharashtra, 441110, India

  • Shree Mahalaxmi DIATONE Institute

    Kohlapur, Maharashtra, 416001, India

  • Siriraj Institute of Clinical Research

    Bangkok, 10700, Thailand

  • Songklanagarind Hospital

    Songkhla, 90110, Thailand

  • TOTALL Diabetes Hormone Institute

    Indore, Madhya Pradesh, 452010, India

  • Thammasat Hospital_CRC

    Pathum Thani, 12120, Thailand

  • ToCROM Clinic_Internal Medicine

    Tokyo, 160-0008, Japan

  • Tokyo-Eki Center-building Clinic_Internal Medicine

    Tokyo, 103-0027, Japan

  • University Malaya Medical Centre

    Lembah Pantai, Kuala Lumpur, 59100, Malaysia

  • Vijan Hospital & Research Centre

    Nashik, Maharashtra, 422005, India

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