MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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Experimental drug combo aims to control resistant blood cancers
Disease control TerminatedThis study aimed to test whether combining two drugs could help control advanced blood cancers that have specific genetic changes and have stopped responding to standard treatments. The trial was designed for adults with myelodysplastic syndromes or related conditions who had alr…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Could a safer dose after transplant help blood cancer patients recover with fewer infections?
Disease control OngoingThis study is testing if using a lower dose of a standard drug (cyclophosphamide) given after a stem cell transplant can reduce serious infections in the first 100 days. The trial aims to see if this lower dose is just as good at preventing graft-versus-host disease, a common and…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New hope for rare blood cancers: drug trial aims to shrink spleens and ease suffering
Disease control OngoingThis study is testing if the drug fedratinib is effective and safe for people with rare, hard-to-treat blood cancers. It will involve about 25 adults with specific conditions like MDS/MPN or chronic neutrophilic leukemia. The main goal is to see if the drug can control the diseas…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Scientists test drug combo to fight tough blood cancer
Disease control OngoingThis study is testing if adding a drug called pomalidomide to standard chemotherapy works better for adults newly diagnosed with a specific, harder-to-treat type of acute myeloid leukemia (AML). About 50 participants will be randomly assigned to receive either the standard chemo …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Oral combo therapy trial aims to control aggressive blood cancers
Disease control OngoingThis study is testing if a two-drug oral combination works better than a single oral drug to control symptoms and reduce cancer cells in patients with certain aggressive blood cancers, including chronic myelomonocytic leukemia (CMML). It is a Phase 2 trial with 132 participants, …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New Triple-Threat treatment tested for aggressive blood cancers
Disease control OngoingThis study is testing a combination of three drugs—azacitidine, venetoclax, and pevonedistat—for adults newly diagnosed with certain high-risk blood cancers. These include acute myeloid leukemia (AML) that developed from other blood disorders or prior cancer treatment, as well as…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Scientists test powerful new drug cocktail for tough blood cancers
Disease control OngoingThis early-stage study aims to find a safe dose for a new combination of three drugs (navitoclax, venetoclax, and decitabine) to treat aggressive forms of blood and bone marrow cancers. It will enroll about 36 adults with specific high-risk conditions like acute myeloid leukemia …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: Jacqueline Garcia, MD • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New hope for tough blood cancers: early drug trial seeks to control disease
Disease control OngoingThis early-stage study is testing a new drug called INCB057643, both alone and in combination with an existing drug (ruxolitinib), in adults with advanced blood cancers like myelofibrosis. The main goal is to check if the treatment is safe and tolerable. Researchers will also loo…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New cell therapy aims to tame transplant dangers for cancer patients
Disease control OngoingThis study is testing a new type of cell therapy for patients with blood cancers or bone marrow diseases who need a stem cell transplant from a partially matched family donor. The goal is to see if adding specially treated immune cells, called 'veto cells,' can help the donor's c…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 19, 2026 15:09 UTC
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New vaccine aims to shield vulnerable cancer patients from dangerous virus
Prevention OngoingThis study is testing a vaccine designed to prevent cytomegalovirus (CMV) infection in adults with blood cancers who are receiving a half-matched stem cell transplant. CMV is a common virus that can become life-threatening when the immune system is weakened after transplant. The …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated Mar 16, 2026 15:25 UTC
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Study reveals hidden toll of blood cancer on daily life
Knowledge-focused OngoingThis study aims to understand how specific blood cancers and their treatments affect patients' daily lives, symptoms, and overall well-being. Researchers are collecting quality-of-life surveys from 572 Italian patients recently diagnosed with these conditions. The goal is to gath…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists hunt for hidden cause of anemia in blood cancer patients
Knowledge-focused OngoingThis study aims to find out how common a specific enzyme problem is in people with certain blood cancers and unexplained anemia. Researchers will take one blood sample from about 100 participants who have conditions like myelodysplastic syndrome (MDS) or other related disorders. …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 06, 2026 15:37 UTC