MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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Triple-Drug cocktail targets Hard-to-Treat blood cancers
Disease control Not yet recruitingThis phase I trial is testing whether combining three drugs—pacritinib, venetoclax, and azacitidine—is safe and tolerable for people with accelerated or blast phase myeloproliferative neoplasms, aggressive blood cancers. The study enrolls about 20 adults whose disease has progres…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jul 02, 2026 01:00 UTC
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New study aims to stop blood cancer relapse after transplant
Disease control Not yet recruitingThis study tests whether giving personalized maintenance therapy after a stem cell transplant can prevent cancer from coming back in people with certain blood cancers. About 450 adults with myeloid cancers who have signs of disease before transplant will be assigned to treatment …
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New combo therapy targets high-risk MDS in early trial
Disease control Not yet recruitingThis study tests a new two-drug combination (pacritinib plus azacitidine) for people with moderate to very high risk myelodysplastic syndrome (MDS), a bone marrow disorder. The first part finds the safest dose of pacritinib, and the second part checks how well the combination wor…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Automated radiation could make stem cell transplants safer for blood cancer patients
Disease control Not yet recruitingThis trial tests a new automated radiation method that precisely targets bone marrow and lymph nodes before a stem cell transplant. The goal is to kill cancer cells while reducing damage to healthy tissues. Participants have high-risk myeloid cancers like acute myeloid leukemia o…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Painless blood test could replace bone marrow biopsy for MPN patients
Diagnosis Not yet recruitingThis study aims to develop a new blood test that could replace the invasive bone marrow biopsy currently used to diagnose myeloproliferative neoplasms (MPNs), a group of blood cancers. Researchers will collect blood samples from 500 adults with suspected or confirmed MPN and anal…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Sponsor: Weizmann Institute of Science • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC