Automated radiation could make stem cell transplants safer for blood cancer patients
NCT ID NCT07634536
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests a new automated radiation method that precisely targets bone marrow and lymph nodes before a stem cell transplant. The goal is to kill cancer cells while reducing damage to healthy tissues. Participants have high-risk myeloid cancers like acute myeloid leukemia or myelodysplastic syndromes. The study will check if this approach is safe and helps patients recover without severe side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Automated total marrow and lymphoid irradiation (TMLI) with fludarabine and cyclophosphamide
- What this could lead to
- If successful, this automated radiation approach could make stem cell transplants safer and more effective for people with high-risk blood cancers.
- What could go wrong
- This is a small, early-phase trial, so results may not apply to all patients. Radiation and chemotherapy still carry risks of serious side effects, including infection and organ damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University
Palo Alto, California, 94304, United States
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