Automated radiation could make stem cell transplants safer for blood cancer patients

NCT ID NCT07634536

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a new automated radiation method that precisely targets bone marrow and lymph nodes before a stem cell transplant. The goal is to kill cancer cells while reducing damage to healthy tissues. Participants have high-risk myeloid cancers like acute myeloid leukemia or myelodysplastic syndromes. The study will check if this approach is safe and helps patients recover without severe side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Automated total marrow and lymphoid irradiation (TMLI) with fludarabine and cyclophosphamide

What this could lead to

If successful, this automated radiation approach could make stem cell transplants safer and more effective for people with high-risk blood cancers.

What could go wrong

This is a small, early-phase trial, so results may not apply to all patients. Radiation and chemotherapy still carry risks of serious side effects, including infection and organ damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome Myelodysplastic Syndromes myelodysplastic/myeloproliferative neoplasm Myeloproliferative Disorders myeloproliferative neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford University

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact