New brain scan may predict chemo brain in young leukemia patients
NCT ID NCT06421155
First seen Jun 24, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This study tests a quick, non-invasive brain scan called Magnetic Resonance Fingerprinting (MRF) in children and young adults with acute leukemia. The goal is to see if the scan can detect early brain changes caused by chemotherapy. Participants also take a fun, game-like memory test on an iPad. The study aims to find ways to prevent long-term thinking and memory problems in survivors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify patients at risk for cognitive side effects from chemotherapy, leading to earlier interventions.
- What could go wrong
- This is a small, early pilot study (20 participants) that is currently suspended. It is designed to test imaging methods, not to prove a treatment benefit.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospitals Cleveland Medical Center, Rainbow Babies & Children's Hospital, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106, United States
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