MILD COGNITIVE IMPAIRMENT

This study is testing if a drug called brivaracetam, normally used for epilepsy, can help people with early Alzheimer's disease or mild memory problems. Researchers suspect some memory loss might be linked to hidden seizure-like activity in the brain. Participants will have brain…

This study is testing a 6-week support program for older adults who have both diabetes and mild memory problems. The program involves their primary caregivers and aims to improve how patients manage their diabetes day-to-day and support their cognitive health. Researchers will me…

This study is testing whether a month of special visual computer exercises can improve mental speed and thinking skills in older adults with mild cognitive impairment. Researchers will compare the exercises to watching regular TV programs to see which helps more. The goal is to f…

This study is testing whether improving deep sleep with gentle sounds can make brain training more effective for people with Parkinson's disease who have mild memory problems. Fifty participants will do a 5-week brain fitness program at home and wear a special headband at night; …

This study is testing whether a non-invasive brain stimulation technique called TMS can boost the brain's natural waste-clearing system. Researchers want to see if this helps remove harmful proteins linked to Alzheimer's disease in people with mild cognitive impairment, an early …

This study is testing whether two different types of computer brain training programs can improve brain health in older adults with mild cognitive impairment (early memory problems). Researchers will enroll about 84 people aged 65+ to complete 35 hours of training over 10 weeks a…

This study is testing whether a 6-month online educational program called Brain Health PRO can help people at risk for dementia improve their lifestyle habits. Researchers will enroll 700 Canadian adults aged 50-80 who have risk factors like family history, high blood pressure, o…

This study is testing if a supervised ketogenic diet (a very low-carb, high-fat eating plan) can help reduce pain and improve thinking in older adults who have both osteoarthritis and mild memory problems. Ten participants will follow the diet, and researchers will check their pa…

This study is testing a modified sleep therapy called SleepSMART, designed specifically for older Veterans who have trouble sleeping and mild memory issues. It compares this new approach to standard sleep therapy to see which is more effective at improving sleep. The goal is to h…

This study is testing whether using a diffuser with a special essential oil blend twice a day for six months can help reduce anxiety, depression, and other difficult symptoms in people with early memory loss or mild dementia. It also aims to see if this approach can lower stress …

This study aims to develop and test a new, adaptive tablet program designed to support thinking skills and social connection for older adults with mild memory problems. Researchers will work with about 290 participants to see if the program is easy to use and helpful in daily lif…

This study is testing whether a virtual reality (VR) program can help older adults with mild memory problems. Researchers want to see if using VR for social and mental activities at home is easy, enjoyable, and helpful for well-being. They will compare the VR program to similar a…

This study is testing if a shorter, 5-week virtual brain training program is just as good as the standard 8-week program for older adults with mild cognitive impairment (MCI). Researchers want to see if the shorter version can still help improve memory, thinking, daily life, and …

This study is testing whether a video game-based exercise program can help older adults in long-term care who have mild memory problems. Researchers want to see if playing these special movement games improves walking, balance, confidence, and the ability to do daily tasks indepe…

This study is testing whether combining a non-invasive brain stimulation technique with virtual reality balance and walking exercises can improve mobility in people with mild cognitive impairment. It will involve 30 adults, half with and half without cognitive issues, who will co…

This study aims to better understand how early memory concerns progress over time in older adults from underserved communities. Researchers will follow 1,000 adults aged 50+ who have been diagnosed with early memory changes but not dementia. Participants will complete annual chec…

This study follows older adults over time to understand how they make decisions about staying in their homes or moving to care facilities as they age, particularly if they develop Alzheimer's disease or memory loss. Researchers will track how factors like health changes, family s…

This study aims to find out if data from wearable devices like smartwatches can help detect early signs of memory problems and Alzheimer's disease. Researchers will enroll 150 adults aged 65 and older, some with early memory concerns and some without, to wear devices that track d…

This study aims to find better ways to detect Alzheimer's disease early, especially in its mild stages, within the Hong Kong community. Researchers will follow 2,500 older adults for 2-3 years, using simple blood tests and comparing them to brain scans. The goal is to see if thes…