LIVER TRANSPLANTATION

This study tested whether a structured program combining exercise, nutritional advice, and psychological support is safe and doable for frail adults with cirrhosis waiting for a liver transplant. Twenty-five participants were enrolled to see if they could stick with the program a…

This study tested whether a 12-week exercise program done at home via video calls could help liver transplant patients regain muscle strength, improve exercise ability, and feel less tired. 140 adults who had a liver transplant took part, with half doing the video-supervised exer…

This study looked at whether giving liver transplant patients simple exercise guides—either a brochure or a video—could help them be more active, feel less tired, and reduce the burden on their caregivers. Over 100 adults who had a liver transplant were split into three groups: o…

This study looked at whether donated livers that were not perfect (called extended criteria donor livers) could be safely used for transplant after being treated with a special machine that pumps fluids through them. The goal was to see if these livers would work well and last a …

This study looked at whether adding thinking tasks to physical exercises helps liver transplant patients improve their memory, balance, and daily function. 32 adults who had a liver transplant were split into two groups: one did standard physiotherapy, the other did motor-cogniti…

This study tested whether very low doses of interleukin-2 (IL-2), given as shots under the skin for 4 weeks, could increase regulatory T-cells (Tregs) in liver transplant recipients. The goal was to see if this could eventually allow patients to take fewer immunosuppressant drugs…

This study tested whether children who had received an organ transplant (kidney, liver, heart, lung, or intestine) could safely switch from taking tacrolimus twice a day (Prograf) to a once-daily version (Advagraf). The goal was to see if the once-daily pill provided similar drug…

This study tested a device that pumps cold, oxygenated fluid through donor livers before transplant. The goal was to see if it reduces early organ damage in livers from older or higher-risk donors. 266 liver transplant patients took part. The approach could help more people get s…

This study tested a new way to treat severe blood clots in the portal vein during liver transplant surgery. Doctors used a special approach through a ligament in the donor liver to place stents or close off abnormal veins. The study included 75 patients and found the method safe …

This study tested whether a special nerve block, called a rectus-intercostal fascial plane block, can reduce pain and the need for morphine in people who donate part of their liver. Sixty-four donors were randomly assigned to receive either the nerve block plus standard painkille…

This study tested whether a nerve block called the external oblique intercostal plane block can reduce pain after liver transplant surgery. Sixty-four adult patients received either the block or a sham procedure after surgery. Researchers measured how much morphine patients neede…

This study tested whether a short virtual reality session could help reduce pain and fatigue in patients who just had a liver transplant. 84 patients were split into two groups: one got a 20-minute VR experience, the other got standard care. Researchers measured pain, fatigue, an…

This study looked at 446 liver transplant patients to see if changes in their MELD score (a measure of liver disease severity) could predict who might not survive. Researchers focused on patients with high MELD scores, who are at greater risk. The goal is to better understand how…

This study tested whether giving free Lyft rides to liver transplant candidates for their medical visits helps them get on the transplant waiting list faster. 261 adults took part. The goal was to see if removing transportation barriers improves access to care.

This study looked back at the records of nearly 7,000 adults who had a liver transplant to see if taking statins beforehand lowered their risk of major heart problems. Researchers checked for events like heart attack, stroke, and heart failure within 30 days after surgery. The go…

This study compared how patients feel about two ways to take a small sample of liver tissue: one using a needle through the skin (percutaneous) and another using a thin tube through the mouth (EUS-guided). 102 adults with chronic liver disease were randomly assigned to one method…

This completed study looked at 3 liver transplant patients to see if muscle loss (sarcopenia) changes how the body responds to the muscle relaxant rocuronium. Researchers measured hand grip strength and used a questionnaire to diagnose sarcopenia before surgery, then tracked how …

This study looked at how the health of caregivers changes when they care for someone getting a liver transplant. 119 caregivers were asked about their tiredness, burden, and physical activity at three times: before the transplant, 90 days after, and 180 days after. The goal was t…

This study aimed to create new mathematical models to better predict which patients with severe liver disease are at highest risk of dying while waiting for a liver transplant. Researchers analyzed data from 501 adults on the French national transplant waiting list. The goal is t…

This study looked back at data from 484 liver cancer patients who had a liver transplant to see if taking certain cancer drugs (tyrosine kinase inhibitors) before the transplant helped them live longer or kept the cancer from coming back. The researchers checked survival rates, c…

This study looked at 82 adults getting a liver transplant to see if using a special blood test called ROTEM helps doctors manage bleeding better than standard tests. The goal was to see if ROTEM could reduce the amount of blood products given during surgery. Researchers tracked c…