New machine may save more livers for transplant patients

NCT ID NCT03929523

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 34 times

Summary

This study tested a special machine that pumps cold, oxygen-rich fluid through donor livers just before transplant. The goal was to see if this method reduces early liver damage after surgery compared to the usual cold storage. The trial included 266 adults receiving a first liver transplant from older or higher-risk donors. If successful, this approach could help more donated livers work well and improve patient outcomes.

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Contacts and locations

Locations

  • APHP - Pitié Salpétrière

    Paris, 75013, France

  • CHU Grenoble Alpes - Department of HPB surgery and liver transplantation

    Grenoble, 38000, France

  • Department of HPB surgery and liver transplantation Beaujon University Hospital

    Clichy, 92210, France

  • Department of HPB surgery and liver transplantation Claude Huriez University Hospital

    Lille, 59037, France

  • Department of HPB surgery and liver transplantation Paul Brousse University Hospital

    Villejuif, 94804, France

  • Department of HPB surgery and liver transplantation Pontchaillou University Hospital

    Rennes, 35033, France

  • Hospices Civils de Lyon

    Lyon, 69004, France

  • Hôpital Hautepierre - Department of HPB surgery and liver transplantation

    Strasbourg, 67200, France

Conditions

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