New machine may help 'Marginal' donor livers work better after transplant
NCT ID NCT03929523
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a device that pumps cold, oxygenated fluid through donor livers before transplant. The goal was to see if it reduces early organ damage in livers from older or higher-risk donors. 266 liver transplant patients took part. The approach could help more people get successful transplants by improving the quality of donated organs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hypothermic Oxygenated Machine Perfusion (HOPE) device
What this could lead to
If it works, this could reduce early liver damage after transplant, helping more patients get successful transplants from older or higher-risk donors.
What could go wrong
This is a completed trial, but results may not apply to all transplant centers or donor types. The device adds time and complexity to the transplant process.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for END STAGE LIVER DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
APHP - Pitié Salpétrière
Paris, 75013, France
-
CHU Grenoble Alpes - Department of HPB surgery and liver transplantation
Grenoble, 38000, France
-
Department of HPB surgery and liver transplantation Beaujon University Hospital
Clichy, 92210, France
-
Department of HPB surgery and liver transplantation Claude Huriez University Hospital
Lille, 59037, France
-
Department of HPB surgery and liver transplantation Paul Brousse University Hospital
Villejuif, 94804, France
-
Department of HPB surgery and liver transplantation Pontchaillou University Hospital
Rennes, 35033, France
-
Hospices Civils de Lyon
Lyon, 69004, France
-
Hôpital Hautepierre - Department of HPB surgery and liver transplantation
Strasbourg, 67200, France