New combo may ease pain after liver transplant

NCT ID NCT06868589

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether giving methadone and ketamine during a deceased donor liver transplant can lower pain and confusion after surgery. About 50 adults will receive either the drug combo or standard care. Researchers will track pain scores, opioid use, and recovery time.

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Conditions

The condition(s) this trial relates to.

Acute Pain chronic liver failure Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01805, United States