New combo aims to ease pain after liver transplant

NCT ID NCT06868589

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests whether giving methadone and ketamine during a liver transplant can lower pain and confusion after surgery. Fifty adults receiving a liver from a deceased donor will be randomly assigned to get either these drugs or standard care. Researchers will track pain scores, opioid use, and delirium during recovery.

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Contacts and locations

Locations

  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01805, United States

Conditions

Explore the condition pages connected to this study.