New pain block could cut opioid use after liver transplant

NCT ID NCT07233083

Completed Symptom relief Sponsor: Istinye University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a nerve block called the external oblique intercostal plane block can reduce pain after liver transplant surgery. Sixty-four adult patients received either the block or a sham procedure after surgery. Researchers measured how much morphine patients needed and their pain scores over the first 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: external oblique intercostal plane block (a nerve block injection)
What this could lead to: If it works, this could offer a better way to manage pain after liver transplant, possibly reducing the need for strong opioids.
What could go wrong: This is a small, completed trial with only 64 participants. The block may not provide significant pain relief over a sham procedure, and results may not apply to all transplant patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic liver failure Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER TRANSPLANTATION POSTOPERATIVE PAIN RECIPIENTS OF LIVER TRANSPLANT

Contacts and locations

Locations

istinye University

Istanbul, Turkey (Türkiye)

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