HEMORRHAGE

This study looked at how well a gel-like material called Obsidio works to block blood vessels in people with hypervascular tumors or bleeding. 125 adults were treated, and researchers checked if the vessels were successfully blocked and if there were any serious side effects with…

This study tested two doses of tranexamic acid (a drug that helps blood clot) to see if it could reduce blood loss during cesarean deliveries when heavy bleeding occurs. 225 women who experienced significant bleeding during a planned or non-emergency C-section were randomly given…

This study looked at 120 patients with severe bleeding who needed a blood transfusion before reaching the hospital. Researchers compared three approaches: giving plasma only, red blood cells only, or a mix of both. The goal was to see which strategy best treats shock and preserve…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the risk of serious bleeding or death in people with blood cancers who have dangerously low platelet counts. Over 600 adults receiving chemotherapy or a stem cell transplant were randomly given eit…

This early study tested the safety of a new spray-dried plasma product called FrontlineODP in 24 healthy volunteers. Participants received increasing doses (1 to 4 units) to see if it causes side effects. The goal is to develop a shelf-stable plasma that can be stored at room tem…

This large study tested whether giving tranexamic acid (TXA) during C-sections can prevent severe bleeding. Over 11,000 women received either TXA or a placebo right after delivery. The goal was to see if TXA reduces the need for blood transfusions or death. Results could change h…

This study tested whether adding a leg compression device to elastic stockings reduces blood clots in intensive care patients at high risk of bleeding. Over 400 patients were randomly assigned to receive either the device plus stockings or stockings alone. The main goal was to se…

This study tested whether giving tranexamic acid (TXA) before tummy tuck surgery reduces blood loss. Sixty adults scheduled for abdominoplasty received either TXA or a placebo before their operation. Researchers measured blood loss, hemoglobin, and other markers to see if TXA hel…

This study tested whether a single dose of tranexamic acid, given before surgery, can reduce blood loss in women undergoing breast cosmetic surgery. 60 women participated, and researchers measured blood loss, hemoglobin, and other clotting factors. The goal is to see if this comm…

This study tested whether a gel called PuraBond, applied to the surgical wound during mouth or throat surgery, can reduce pain and bleeding afterward. 73 patients were randomly assigned to receive the gel or not. Researchers measured pain levels over 30 days and tracked complicat…

This study tests whether a device called Mostcare can predict if children need more fluids after surgery. Researchers will compare its readings with ultrasound measurements in 100 children aged 0-10 who are on breathing machines. The goal is to see if the device can help doctors …

This study looked at whether a new, rapid blood test called Quantra can reliably measure bleeding risk during heart surgery. Researchers compared Quantra results to standard lab tests in 600 adults having heart surgery with a heart-lung machine. The goal was to see if Quantra cou…

This study looked at 217 Dutch patients who were hospitalized with serious bleeding while taking a type of blood thinner called a factor Xa inhibitor. All patients received a drug called andexanet alfa to reverse the bleeding. Researchers wanted to learn more about the patients' …

This study tested a digital platform that helps hospital staff quickly identify patients who are bleeding, so they can be asked to join future research studies. About 40 adults admitted to Oxford University Hospitals took part. The goal was to see if the platform could correctly …

This study looked at 15 stroke patients with a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All patients received a clot-busting drug (thrombolysis) and were checked for brain bleeding 24 hours later. Re…

This study tested a mixed-reality simulator that uses a virtual coach to train medical professionals in a procedure called REBOA, which controls severe bleeding. Fourteen participants were trained either by the virtual coach or a human instructor. The goal was to see if the virtu…

This study tested new MRI methods to detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 patients to see if these scans could better identify damage that raises the risk of heart failure. The goal was to improve imaging, not to test a treatment.