HEMORRHAGE

This study tested whether tranexamic acid (TXA), a drug that helps blood clot, can reduce blood loss during breast cosmetic surgery. Sixty women having breast surgery took part. Researchers measured blood loss and checked blood markers before and after surgery to see if TXA helpe…

This study looked at 120 people with severe bleeding who needed a blood transfusion before reaching the hospital. Researchers compared three approaches: giving a mix of plasma and red blood cells, red blood cells alone, or plasma alone. The goal was to see which strategy best hel…

This study looked at how well and how safely the Obsidio device blocks blood vessels to control bleeding from hypervascular tumors. It involved 125 patients in the U.S. who were treated with Obsidio. The main goals were to see if the device successfully blocked the target vessels…

This study tested two doses of tranexamic acid, a drug that helps blood clot, to see if it could reduce blood loss in women having a C-section who were already bleeding heavily (over 800 mL). The trial involved 225 participants and compared the drug to a placebo. The goal was to …

This study tested whether a drug called tranexamic acid (TXA) can reduce blood loss during tummy tuck surgery. Sixty adults having a tummy tuck were given either TXA or a placebo. The goal was to see if TXA helps control bleeding and improve recovery.

This study tested whether a drug called tranexamic acid can lower the risk of serious bleeding or death in people with blood cancers who have very low platelet counts. Over 600 adults receiving chemotherapy or a stem cell transplant were given either the drug or a placebo. The go…

This study looked at whether using intermittent pneumatic compression (a device that squeezes the legs) along with elastic stockings reduces blood clots in the legs or lungs better than stockings alone. It included 408 adults in intensive care who were at high risk for bleeding. …

This study tested whether applying a special gel (PuraBond) to the surgical wound after mouth surgery could reduce pain and complications. 73 adults having surgery for mouth or throat lesions were randomly assigned to receive the gel or not. The main goal was to see if the gel lo…

This early-stage study tested the safety of a new spray-dried plasma product called FrontlineODP in 24 healthy adults. Participants received one, two, or four units of the product, and their safety was compared to those receiving standard frozen plasma. The goal was to see if the…

This study looked at 600 heart surgery patients to see if a new device called Quantra can quickly and accurately measure bleeding risk. The goal was to check if Quantra results match standard lab tests for clotting, fibrinogen, and platelets. The study did not test a treatment, b…

This study tested a mixed-reality simulator that uses a virtual coach to teach a life-saving emergency procedure called REBOA. The goal was to see if the virtual coach could train people as well as a human instructor. Fourteen adults participated, and the study compared how quick…

This study tested new MRI methods to better detect bleeding inside heart muscle after a heart attack. Researchers studied 14 adults who had a heart attack to see if these scans could map the bleeding more clearly. The goal is to help doctors identify patients at higher risk for h…

This study looked at 15 stroke patients who had a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All patients received a clot-busting drug (thrombolysis) for their stroke. Researchers checked CT scans 24 h…

This study reviewed medical records of 217 Dutch adults hospitalized with severe bleeding while taking a factor Xa inhibitor blood thinner. All patients received andexanet alfa to reverse the bleeding. Researchers wanted to understand patient characteristics and outcomes, includi…

This study tested a digital platform called RE-BLEED to quickly identify patients with bleeding in the hospital. Researchers wanted to see if the system could help recruit participants for future studies. The study included 40 adults admitted to the hospital or emergency departme…