Can a common drug make C-Sections safer? new trial tests lower dose

NCT ID NCT02797119

Completed Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two doses of tranexamic acid (a drug that helps blood clot) to see if it could reduce blood loss during cesarean deliveries when heavy bleeding occurs. 225 women who experienced significant bleeding during a planned or non-emergency C-section were randomly given either a standard dose, a half-dose, or a placebo. The goal was to find the best balance between stopping bleeding and avoiding side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tranexamic acid
What this could lead to: If successful, this could help doctors choose the safest effective dose of tranexamic acid to reduce dangerous bleeding during C-sections.
What could go wrong: This is a completed Phase 4 trial with 225 participants, so results are reliable but may not apply to all types of bleeding or emergency C-sections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEMORRHAGE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hemorrhage pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMORRHAGE PREGNANCY COMPLICATIONS

Contacts and locations

Locations

Assistance Publique Hôpitaux Paris Hôpital Louis Mourier

Paris, France
Assistance Publique Hôpitaux Paris Hôpital Trousseau

Paris, France
Centre Hospitalier Maternité Monaco Valenciennes

Valenciennes, France
Hospices civils de Lyon CHU-Lyon Croix Rousse

Lyon, France
Hôpital Jeanne de Flandre - CHRU de Lille

Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.