Can a common drug make C-Sections safer? new trial tests lower dose
NCT ID NCT02797119
First seen Apr 25, 2026 · Last updated Jun 22, 2026 · Updated 11 times
Summary
This study tested two doses of tranexamic acid (a drug that helps blood clot) to see if it could reduce blood loss during cesarean deliveries when heavy bleeding occurs. 225 women who experienced significant bleeding during a planned or non-emergency C-section were randomly given either a standard dose, a half-dose, or a placebo. The goal was to find the best balance between stopping bleeding and avoiding side effects.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assistance Publique Hôpitaux Paris Hôpital Louis Mourier
Paris, France
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Assistance Publique Hôpitaux Paris Hôpital Trousseau
Paris, France
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Centre Hospitalier Maternité Monaco Valenciennes
Valenciennes, France
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Hospices civils de Lyon CHU-Lyon Croix Rousse
Lyon, France
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Hôpital Jeanne de Flandre - CHRU de Lille
Lille, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If successful, this could help doctors choose the safest effective dose of tranexamic acid to reduce dangerous bleeding during C-sections.
What could go wrong
This is a completed Phase 4 trial with 225 participants, so results are reliable but may not apply to all types of bleeding or emergency C-sections.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.