Ultrasound may predict hidden placental problems before delivery

NCT ID NCT06022458

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The trial has finished. Results may not be published yet.
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Cancelled before anyone took part.

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First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This observational study investigates whether prenatal ultrasound can predict placental abnormalities found after delivery. Researchers will compare imaging features from 320 pregnancies with and without placental pathology. The goal is to improve detection of placental issues that may affect pregnancy outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better prenatal monitoring and earlier detection of placental issues, improving outcomes for pregnant people and their babies.
What could go wrong
This is an observational study, not a treatment trial. It may not find a strong link between ultrasound images and actual placental problems, limiting its impact.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 320 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pregnant patients who plan to deliver at NorthShore University HealthSystem

Ages

18 to 60 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Retrospective Phase Inclusion criteria: * Patients with delivery in NorthShore University HealthSystem, * Ultrasound available within 4 weeks of delivery with adequate placental images * Placental pathology available Exclusion criteria: * Multiple gestation Prospective Phase Inclusion criteria * Exposed: Patients with singleton gestation with fetal growth restriction at 20-28 weeks with a plan to deliver at NorthShore Highland Park Hospital Evanston Hospital. Patients must have a first-trimester ultrasound (\<14 weeks) to confirm pregnancy dating available in the electronic medical record. * Unexposed: Patients who present for routine ultrasound evaluation at 36-38 weeks with normal fetal growth with a plan to deliver at NorthShore Highland Park Hospital or NorthShore Evanston Hospital. Exclusion criteria: * Exposed: Multiple gestation, major fetal anomaly * Unexposed: Multiple gestation, history of chronic hypertension, gestational or pregestational diabetes, major fetal anomaly antiphospholipid syndrome, known thrombophilia

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • NorthShore University HealthSystem

    RECRUITING

    Evanston, Illinois, 60201, United States

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