HEMORRHAGE

This study was designed to see if giving calcium right away to trauma patients who need large blood transfusions could help their blood clot better, reduce the need for more transfusions, and improve survival. The trial was withdrawn before enrolling any participants, so no resul…

This study was designed to test the safety and tolerability of a new drug called HMPL-523 (sovleplenib) in adults with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding problems. The trial was withdrawn before enrolling any pa…

This registry will follow 500 adults who receive the LOBO Vascular Occlusion System, a device used to block blood vessels in cases of arterial bleeding or other conditions. The goal is to see how safe and effective the device is in everyday medical practice. Participants are enro…

This study follows 350 people who survived a brain bleed (intracerebral hemorrhage) and were part of earlier trials. Researchers will test memory, thinking, and movement skills over time, and collect blood samples to look for signs of ongoing inflammation. The goal is to see if s…

This study tests whether having a specialist give advice by phone during emergencies helps patients with severe bleeding who take blood thinners. About 1,000 patients will be treated either with standard care or with added expert guidance. Researchers will compare how well bleedi…

This study compares how well different tourniquet models block blood flow when placed on the arm, forearm, leg, and thigh. Forty healthy volunteers will each receive eight tourniquet applications over three days. The goal is to see if placement location affects how quickly and co…

This study uses ultrasound to measure heart changes in 66 healthy blood donors before and after giving blood. The goal is to see if a simple, non-invasive test can detect mild blood loss. If it works, it could help doctors spot internal bleeding early in trauma patients.