New powdered plasma shows promise in early safety trial

NCT ID NCT05629338

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tested the safety of a new spray-dried plasma product called FrontlineODP in 24 healthy volunteers. Participants received increasing doses (1 to 4 units) to see if it causes side effects. The goal is to develop a shelf-stable plasma that can be stored at room temperature for emergency bleeding situations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Spray-dried plasma (FrontlineODP)

What this could lead to

If safe, this could lead to a shelf-stable plasma product for treating bleeding in emergencies, especially where fresh plasma is unavailable.

What could go wrong

This is a very early Phase 1 safety study in only 24 healthy people, not patients. It does not test effectiveness, and side effects may still emerge.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease Hemorrhage vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hoxworth Blood Center

    Cincinnati, Ohio, 45267-0055, United States

  • Spaulding Clinical Research LLC

    West Bend, Wisconsin, 53095, United States

  • Versiti Blood Center of Wisconsin

    Milwaukee, Wisconsin, 53233, United States