ENDOMETRIOSIS

This study aims to see if an investigational drug called HMI-115 can safely reduce moderate to severe pain caused by endometriosis. It will involve about 540 women who will receive either the drug or a placebo for 24 weeks, with an option to continue for another 28 weeks. The mai…

This study aims to see how well a specific oral hormone therapy (relugolix combination therapy) works for reducing pelvic pain in women with endometriosis during routine medical care. It will follow about 33 women for 24 weeks to measure changes in their pain levels and other sym…

This study will compare two surgical approaches for removing the uterus for benign (non-cancerous) conditions like fibroids or heavy bleeding. Researchers will follow 500 patients for three years to see which method—total removal or partial removal—leads to better long-term quali…

This study is testing a new surgical method called laparoscopic sclerotherapy to treat ovarian cysts caused by endometriosis. Instead of cutting out the cyst wall, surgeons drain the cyst and fill it with a concentrated alcohol solution to shrink it. The main goal is to see if th…

This study is testing whether following a Mediterranean diet can reduce pain and improve quality of life for women with endometriosis. Researchers believe the diet's anti-inflammatory properties may help ease symptoms. The study will involve 104 women who will track their pain le…

This study is testing whether a portable, non-drug device called actiTENS mini can help reduce chronic pelvic pain in women with endometriosis. It will involve 208 women across 27 centers in France. Participants will use the device daily for several months, comparing different st…

This study is testing whether a special magnetic stimulation chair can help reduce chronic pelvic pain in women with endometriosis. Researchers will enroll 30 women who still experience significant pain despite standard treatments. Participants will receive 12 sessions in the 'Te…

This study is testing whether a TENS device, which uses gentle electrical pulses on the skin, can help manage the chronic pelvic pain caused by endometriosis. It will involve about 92 women who still have pain despite their current hormone treatment. The goal is to see if this no…

This study aims to see if a series of electroacupuncture treatments can reduce pelvic pain in women with suspected endometriosis. Thirty-eight women scheduled for diagnostic surgery will be randomly assigned to receive either the acupuncture treatment or standard care. The goal i…

This study is testing a new device called Hyivy, which is used at home, to see if it can help reduce chronic pelvic pain in people with endometriosis. It's a small, early-stage study looking at whether the device is safe, easy to use, and if it can lessen pain and improve daily l…

This study aims to see if different types of psychological support can improve the quality of life and mental health for women living with endometriosis. It will compare individual therapy, group therapy, and a combination of both against no treatment. The goal is to find the bes…

This study is testing if adding the drug ketamine to standard anesthesia during endometriosis surgery helps reduce pain in the hours and weeks after the operation. About 126 women having outpatient surgery will be randomly assigned to receive anesthesia with or without ketamine. …

This study is testing whether a specialized 'good pain consultation' helps women with endometriosis better manage their chronic pelvic pain. Researchers will compare this new consultation, which includes education on the physical and emotional aspects of pain, to the usual medica…

This study aims to understand if exposure to certain long-lasting industrial chemicals in the environment is linked to more severe endometriosis. Researchers will measure levels of these chemicals in the blood of 650 women with endometriosis and compare them to the severity of th…

This study aims to understand why some women experience repeated IVF failures or miscarriages. Researchers will compare uterine tissue and blood samples from women with these histories to women without them, looking for differences in immune cells and bacteria. The goal is to ide…

This study looks at how patients using AI tools like ChatGPT to prepare for endometriosis doctor visits affects their experience and care. Researchers will compare women who use AI before their appointment to those who don't, measuring satisfaction, treatment adherence, and docto…

This study aims to understand how endometriosis changes over time and how it affects patients' lives. Researchers will follow 100 women with diagnosed endometriosis for two years, using regular ultrasounds and questionnaires to track their symptoms and quality of life. The goal i…

This study aims to find out if women with chronic pelvic pain that doesn't get better with standard hormone treatments have a specific pattern in their immune system. Researchers will take blood samples from 120 women and measure different immune system signals to see if a unique…

This study aims to create the first-ever lab-grown cells from the human diaphragm, the main breathing muscle. Researchers will collect small tissue samples from 10 people undergoing surgery for a separate condition. By comparing these new diaphragm cells to existing arm muscle ce…

This study aims to understand how the immune system and gut bacteria are involved in endometriosis, a painful condition affecting many women. Researchers will compare tissue and stool samples from 40 women with endometriosis to samples from women without it. The goal is to find b…

This study aims to discover biological markers in women with moderate to severe endometriosis. Researchers will collect fluid and tissue samples from 90 participants to understand how endometriosis affects fertility. The findings may help develop better diagnostic tools and futur…

This study aims to understand if having deep endometriosis in the bowel increases a person's risk of developing colorectal cancer. Researchers will enroll 30 female patients who are already scheduled for surgery to treat their bowel endometriosis. They will compare the genetic ac…