Scientists grow diaphragm cells to battle fatal muscle diseases

NCT ID NCT07380308

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a new lab model of human diaphragm muscle cells using tissue from women undergoing surgery for diaphragmatic endometriosis. Researchers will compare these cells to arm muscle cells to understand what makes the diaphragm unique. The goal is to provide a tool for studying diseases like ALS that cause respiratory failure, potentially opening doors to future treatments. Only 10 participants are needed, and no new drugs or procedures are being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could provide a new lab tool to study diaphragm muscle wasting in diseases like ALS, potentially pointing toward future therapies.
What could go wrong: This is a very early, small study (10 people) focused on basic research, not a treatment trial. It may not lead to any direct medical benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS

Contacts and locations

Locations

Department of Thoracic Surgery - Cochin Hospital

Paris, IDF, 75014, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.