Could a common muscle relaxant cut narcotic use after hysterectomy?

NCT ID NCT07664956

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding cyclobenzaprine, a muscle relaxant, to standard pain medicines (ibuprofen, acetaminophen, and short-term narcotics) improves pain control and reduces narcotic use after minimally invasive hysterectomy. About 36 women undergoing laparoscopic hysterectomy will be randomly assigned to receive either cyclobenzaprine or a placebo for one week after surgery. Pain scores and medication use will be tracked.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Cyclobenzaprine (a muscle relaxant)
What this could lead to
If it works, this could offer a better pain management option after hysterectomy, reducing the need for narcotics.
What could go wrong
This is a small, early-phase trial with only 36 participants, so results may not apply widely. The benefit may be small or not statistically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ChristianaCare Health System

    Newark, Delaware, 19718, United States

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