Could a common muscle relaxant cut narcotic use after hysterectomy?
NCT ID NCT07664956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding cyclobenzaprine, a muscle relaxant, to standard pain medicines (ibuprofen, acetaminophen, and short-term narcotics) improves pain control and reduces narcotic use after minimally invasive hysterectomy. About 36 women undergoing laparoscopic hysterectomy will be randomly assigned to receive either cyclobenzaprine or a placebo for one week after surgery. Pain scores and medication use will be tracked.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cyclobenzaprine (a muscle relaxant)
What this could lead to
If it works, this could offer a better pain management option after hysterectomy, reducing the need for narcotics.
What could go wrong
This is a small, early-phase trial with only 36 participants, so results may not apply widely. The benefit may be small or not statistically significant.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ChristianaCare Health System
Newark, Delaware, 19718, United States