DOWN SYNDROME

This study tested whether the drug tofacitinib is safe and effective for treating several common autoimmune skin conditions in adolescents and adults with Down syndrome. Researchers wanted to see if reducing overactive immune signaling could improve skin health, quality of life, …

This study tested whether dilating the eyes (using drops to widen the pupil) gives a better measurement for glasses prescriptions in people with Down syndrome. People with Down syndrome often have unique eye shapes that make standard vision tests less accurate. Researchers compar…

This study tested whether a simple blood test from the mother could safely replace invasive procedures for detecting Down syndrome. Researchers compared the new blood test against standard invasive tests in over 2,000 pregnant women at higher risk. The goal was to see if the bloo…

This study tested whether a 12-week online group dance program is a practical and acceptable way to help young adults with Down syndrome get more physical activity. The goal was to see if this fun, social exercise could be a feasible strategy to help delay the onset of Alzheimer'…

This study compared two different therapies—orofacial (face and mouth) exercises and therapeutic yoga—to see which one better helps children with Down syndrome. Thirty children, aged 5 to 12, were randomly assigned to receive one of the therapies along with their usual physical t…

This study tested whether a specific diet plan combined with nutritional supplements could help improve thinking skills, sleep quality, and body function in children and young adults with Down syndrome, autism, or ADHD. It involved 76 participants aged 2 to 35 who followed the pr…

This study adapted a Turkish version of a trunk control assessment scale for infants with Down syndrome. Researchers tested the tool's accuracy and consistency in measuring how well babies control their torso during sitting and movement. The goal is to help therapists better trac…

This study aimed to find signs that could help doctors predict and diagnose sleep apnea earlier in people with Down syndrome. Researchers studied 40 adults with Down syndrome, looking at factors like facial structure, physical activity levels, and heart function during sleep. The…

This study aimed to understand why people with Down syndrome often have very low fitness levels. Researchers tested whether a 12-week supervised exercise program could improve how the body regulates blood flow to the heart and muscles during activity. They measured changes in fit…

This study explored whether specific training could improve spatial thinking skills—like mentally rotating objects or understanding different viewpoints—in people with Down syndrome. Researchers worked with 84 participants, including adolescents and young adults with Down syndrom…

This study tested whether an 8-week online nutrition education program could improve eating habits for people with Down syndrome and increase their caregivers' nutrition knowledge. It involved 31 individuals with Down syndrome and their 31 caregivers in Turkey. Researchers measur…

This study aimed to understand why parents on Reunion Island in France often choose to continue a pregnancy after learning their baby will have Down Syndrome, when national data shows most choose termination. Researchers interviewed 28 parents who had a child with Down Syndrome t…

This research study aimed to understand if specific movement exercises could help babies with Down syndrome develop thinking and language skills. Researchers worked with 51 infants to test whether practicing walking on a small treadmill or using special 'sticky mittens' to practi…

This study aimed to create a new survey tool to measure health in people with Down syndrome. Researchers worked with caregivers, individuals with Down syndrome, and doctors to develop and test the survey. The goal is to better understand health needs and improve care for this com…