DOWN SYNDROME

This study tested an 8-week online nutrition education program for 31 people with Down syndrome and their 31 caregivers. The program aimed to improve eating habits and health. Results showed changes in dietary behavior and nutrient intake after the program.

This study tested whether tofacitinib, a drug already approved for other conditions, is safe and helpful for people with Down syndrome who also have immune-related skin problems like eczema, psoriasis, or hair loss. The study included 47 adolescents and adults. Researchers measur…

This study looked at whether a simple blood test (NIPT) can safely replace the standard invasive test for Down syndrome in pregnant women at higher risk. Over 2,100 women were randomly assigned to either the blood test or the usual needle test. The goal was to see if the blood te…

This study compared two non-drug treatments—orofacial therapy (exercises for the mouth and face) and therapeutic yoga—in 30 children with Down syndrome aged 5 to 12. The goal was to see which approach better improves swallowing, sleep habits, and overall quality of life. Research…

This study looked at whether dilating (widening) the eyes before measuring vision helps create better eyeglass prescriptions for people with Down syndrome. Many people with Down syndrome have unusual eye shapes that standard tests miss, leading to blurry glasses. The researchers …

This study tested whether virtual reality exercise (exergaming) is as good as or better than traditional aerobic exercise for improving physical fitness, daily function, and thinking skills in people with Down syndrome. 44 participants with mild to moderate intellectual disabilit…

This study tested a special diet and nutritional supplement in 76 people aged 2 to 35 with Down syndrome, autism, or ADHD. The goal was to see if this approach could improve thinking skills, sleep quality, and overall health. Participants followed a modified diet and took the sup…

This study tested a behavioral therapy called JASPER in 103 children with Down syndrome, ages 3 to 7. Caregivers received coaching to help their child improve joint attention, play, and social communication. The goal was to see if this approach helps children engage more and deve…

This study tested a program called Babble Boot Camp for infants with Down syndrome, who often start talking late. 60 babies under 12 months old took part. Parents were trained by a speech therapist via video calls to do simple activities at home. The goal was to see if this early…

This study looked at how early motor skills (like reaching and crawling) affect thinking, language, and gestures in 51 infants with Down syndrome, ages 7 to 36 months. Researchers measured cognitive and language development, as well as gesture use, to see if movement experience h…

This study looked for early warning signs of sleep apnea in people with Down syndrome. Sleep apnea is common in this group but often missed, and it can harm the heart and brain. Researchers studied 40 adults with Down syndrome using sleep tests and heart monitoring to find factor…

This study looked at how young children with Down syndrome, cerebral palsy, or other motor delays first use mobility devices like a bodyweight support system and a powered wheelchair. Researchers measured how much of a play space the children explored and their muscle activity. T…

This study looked at whether people with Down syndrome can improve their spatial abilities—like mentally rotating objects or seeing another person's point of view—through hands-on activities such as puzzles, block building, and computer games. 84 participants (adolescents and you…

This study translated and tested a trunk control assessment (SATCo) for Turkish infants with Down syndrome. Researchers worked with 27 infants to see if the test is valid and reliable. The goal is to better understand motor development in these children.

This study tested whether a 12-week online dance program is practical and enjoyable for young adults with Down Syndrome. Twenty participants joined two 35-minute group dance sessions each week from home. Researchers measured attendance, safety, and changes in fitness and thinking…

This study developed a new questionnaire called the Down Syndrome Health Instrument (DHI) to measure health in people with Down syndrome. Researchers worked with caregivers, individuals with Down syndrome, and doctors to create and test the tool. Over 750 participants took part i…

This study looked at how a 13-week exercise program changes blood flow and fitness in 60 adults with Down syndrome who were not very active. Researchers measured how well the heart and blood vessels worked during exercise. The goal was to learn more about why people with Down syn…

This study interviewed 28 parents in Reunion Island who had a child with Down syndrome to understand why they chose not to have a medical termination of pregnancy. Researchers wanted to learn about the beliefs, values, and cultural or economic factors that influenced their decisi…