DOWN SYNDROME
Clinical trials for DOWN SYNDROME explained in plain language.
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Could a higher dose of an Alzheimer's drug boost thinking skills in down syndrome?
Symptom relief Not yet recruitingThis early-stage trial will test whether higher-than-standard doses of memantine, a drug already approved for Alzheimer's, are safe and tolerable in 25 adolescents and young adults with Down syndrome. The study also looks for early signs that the drug might improve memory and thi…
Matched conditions: DOWN SYNDROME
Phase: PHASE1 • Sponsor: University Hospitals Cleveland Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Bouncing to better breathing: trampoline therapy tested for down syndrome kids
Symptom relief Not yet recruitingThis study tests whether adding mini-trampoline exercises (rebound therapy) to standard chest physical therapy can improve lung function in children with Down syndrome. Forty children aged 9 to 13 will be randomly assigned to either chest therapy alone or chest therapy plus rebou…
Matched conditions: DOWN SYNDROME
Phase: NA • Sponsor: Beni-Suef University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Parenting a child with down syndrome? new study tests resilience training to ease burden
Symptom relief Not yet recruitingThis study tests whether a resilience training program can help parents of young children with Down syndrome feel more accepting and less burdened. About 50 parents will be randomly assigned to either the training or usual care. Researchers will measure changes in acceptance, rej…
Matched conditions: DOWN SYNDROME
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Could a natural compound sharpen minds of kids with down syndrome?
Symptom relief Not yet recruitingThis study tests whether a natural compound called phenolic complex k110-42 can improve attention and thinking in children with Down syndrome. About 108 children aged 4 to 8 will take the compound and have their cognitive skills measured with standard tests. The goal is to ease s…
Matched conditions: DOWN SYNDROME
Phase: PHASE3 • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can a special walker help babies with down syndrome take their first steps?
Knowledge-focused Not yet recruitingThis study looks at whether a suspension walker is a practical tool for pre-walking infants with Down syndrome to use at home. Twelve infants aged 10-13 months will try using the walker for 20 minutes a day, 5 days a week over three months. Researchers want to see if families can…
Matched conditions: DOWN SYNDROME
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC